Osteoporosis: Clinical features, prevention, and treatment

S. R. Gambert, B. M. Schultz, R. C. Hamdy

Research output: Contribution to journalReview article


Osteoporosis is a significant and growing problem among the elderly. Although therapies exist to treat established disease, preventive measures that maintain bone mass throughout life are preferable. Osteoporosis is a condition resulting in an increased risk of skeletal fractures owing to a reduction in the volume of bone tissue. There is a preservation of the normal ratio of unmineralized-to-mineralized bone matrix. This disease affects postmenopausal women most frequently, and a link clearly exists between estrogen deficiency and accelerated bone loss. Diet, exercise, and other forms of treatment exist for well-established disease.

Original languageEnglish (US)
Pages (from-to)317-371
Number of pages55
JournalEndocrinology and metabolism clinics of North America
Issue number2
StatePublished - Jan 1 1995


ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Gambert, S. R., Schultz, B. M., & Hamdy, R. C. (1995). Osteoporosis: Clinical features, prevention, and treatment. Endocrinology and metabolism clinics of North America, 24(2), 317-371.