Osteopathic Manipulative Therapy and Multiple Sclerosis: A Proof-of-Concept Study

Christian Cordano, Annalisa Armezzani, Jacopo Veroni, Matteo Pardini, Davide Sassos, Maria Teresa Infante, Andrea Tacchino, Caterina Lapucci, Maria Cellerino, Valentina Calabrò, Luigi Ciullo, Bardia Nourbakhsh

Research output: Contribution to journalArticlepeer-review

Abstract

Context: Research on the effect of osteopathic manipulative therapy (OMTh; manipulative care provided by foreign-trained osteopaths) on chronic symptoms of multiple sclerosis (MS) is lacking. Objective: To evaluate the effect of OMTh on chronic symptoms of MS. Methods: Patients with MS who were evaluated at the neurology clinic at Genoa University in Italy were recruited for this study. Participants received 5 forty-minute MS health education sessions (control group) or 5 OMTh sessions (OMTh group). All participants completed a questionnaire that assessed their level of clinical disability, fatigue, depression, anxiety, and quality of life before the first session, 1 week after the final session, and 6 months after the final session. The Extended Disability Status Scale, a modified Fatigue Impact Scale, the Beck Depression Inventory-II, the Beck Anxiety Inventory, and the 12-item Short Form Health Survey were used to assess clinical disability, fatigue, depression, anxiety, and quality of life, respectively. Results: Twenty-two participants were included in the study (10 in the control group and 12 in the OMTh group). In the OMTh group, statistically significant improvements in fatigue and depression were found 1 week after the final session (P=.002 and P<.001, respectively). An increase in quality of life was also found in the OMTh group 1 week after the final session (P=.36). Conclusion: Results demonstrate that OMTh should be considered in the treatment of patients with chronic symptoms of MS.

Original languageEnglish (US)
Pages (from-to)531-536
Number of pages6
JournalThe Journal of the American Osteopathic Association
Volume118
Issue number8
DOIs
StatePublished - Aug 1 2018

ASJC Scopus subject areas

  • Complementary and alternative medicine

Fingerprint Dive into the research topics of 'Osteopathic Manipulative Therapy and Multiple Sclerosis: A Proof-of-Concept Study'. Together they form a unique fingerprint.

Cite this