Abstract
The complete genomes of the yeast Saccharomyces cerevisiae and the nematode worm Caenorhabditis elegans have recently become available allowing the comparison of the complete protein sets of a unicellular and multicellular eukaryote for the first time. These comparisons reveal some striking trends in terms of expansions or extensive shuffling of specific domains that are involved in regulatory functions and signaling. Similar comparisons with the available sequence data from the plant Arabidopsis thaliana produce consistent results. These observations have provided useful insights regarding the origin of multicellular organisms.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 688-694 |
| Number of pages | 7 |
| Journal | Current Opinion in Genetics and Development |
| Volume | 9 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1 1999 |
ASJC Scopus subject areas
- Genetics
- Developmental Biology
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Cite this
Aravind, L., & Subramanian, G. (1999). Origin of multicellular eukaryotes - Insights from proteome comparisons. Current Opinion in Genetics and Development, 9(6), 688-694. https://doi.org/10.1016/S0959-437X(99)00028-3