Origin of chromosome rearrangements in two long-lived human keratinocyte lines

C. Rosenberg, G. Stetten, W. G. Kearns, P. L. Pearson, J. W. Littlefield

Research output: Contribution to journalArticle

Abstract

We have determined the origin of the extra chromosomal material in the karyotypes of two spontaneously-occurring long-lived human keratinocyte lines, HKC-N2 and HKC-N6. In each case the extra material was derived from the chromosome on which it was located. Possible relationships between the triplication of chromosomal material and the overcoming of cell senescence are discussed.

Original languageEnglish (US)
Pages (from-to)823-825
Number of pages3
JournalIn Vitro Cellular and Developmental Biology - Animal
Volume27 A
Issue number10
DOIs
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Developmental Biology
  • Clinical Biochemistry
  • Cell Biology

Fingerprint Dive into the research topics of 'Origin of chromosome rearrangements in two long-lived human keratinocyte lines'. Together they form a unique fingerprint.

  • Cite this

    Rosenberg, C., Stetten, G., Kearns, W. G., Pearson, P. L., & Littlefield, J. W. (1991). Origin of chromosome rearrangements in two long-lived human keratinocyte lines. In Vitro Cellular and Developmental Biology - Animal, 27 A(10), 823-825. https://doi.org/10.1007/BF02631249