Organization, development and early results of a heart transplant program. The Johns Hopkins Hospital Experience

W. A. Baumgartner, A. M. Borkon, S. C. Achuff, K. L. Baughman, T. A. Traill, B. A. Reitz

Research output: Contribution to journalArticle

Abstract

Improved survival and quality of life have resulted in a resurgence in cardiac transplantation and the proliferation of centers contemplating initiation of a transplant program. Organization of such a program requires cooperation among several clinical and non-clinical departments of the hospital. Prior to implementation of such a program, a number of issues need to be addressed, including state authorization, an expeditious method for donor organ retrieval, protocols for recipient selection and evaluation, and perioperative and follow-up care of the transplant recipient. Since July of 1983, 35 patients (27 men and eight women) have undergone orthotopic cardiac transplantation. Transplantation was undertaken for cardiomyopathy (30) or end-stage ischemic heart disease (5). The mean age was 38 years (range, 16 to 57 yrs). Distant organ procurement was used for 83 percent of patients; mean ischemic time was 164 min (range, 75 to 250 min). Current immunosuppressive regimen consists of oral cyclosporine (10 mg/kg) and prednisone. Mean follow-up was 10.3 months (range, two weeks to 27 months). Transient renal dysfunction appeared early in 15 patients. Six deaths have occurred: three from rejection, one from infection, one from metastatic prostate carcinoma, and one from pulmonary hemorrhage. All but three recent patients have been rehabilitated. These initial encouraging results are a result of careful planning, institutional commitment, adequate resources and, most importantly, a dedicated transplant team.

Original languageEnglish (US)
Pages (from-to)836-839
Number of pages4
JournalChest
Volume89
Issue number6
StatePublished - 1986

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Organizations
Transplants
Heart Transplantation
Tissue and Organ Harvesting
Aftercare
Tissue and Organ Procurement
Hospital Departments
Immunosuppressive Agents
Prednisone
Cardiomyopathies
Cyclosporine
Myocardial Ischemia
Prostate
Transplantation
Quality of Life
Tissue Donors
Hemorrhage
Carcinoma
Kidney
Lung

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Organization, development and early results of a heart transplant program. The Johns Hopkins Hospital Experience. / Baumgartner, W. A.; Borkon, A. M.; Achuff, S. C.; Baughman, K. L.; Traill, T. A.; Reitz, B. A.

In: Chest, Vol. 89, No. 6, 1986, p. 836-839.

Research output: Contribution to journalArticle

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