Organization and Heterogeneity of Sequences within a Repeating Unit of Human Y Chromosome Deoxyribonucleic Acid

Samuel H. Boyer, Kirby D. Smith, Louis M. Kunkel

Research output: Contribution to journalArticlepeer-review

Abstract

Fragments of 3.4 kilobases (kb) are released from DNA of human males, but not DNA of human females, by cleavage with restriction endonucleases HaeIII, EcoRI, or EcoRII. Most, if not all, reiterated DNA which is specific for the Y chromosome (it-Y DNA) is present within these male-specific 3.4-kb molecules. Although such 3.4-kb molecules are themselves localized to the Y chromosome, this is not true for all sequences within them. At least two distinguishable types of reiterated sequences are found within each 3.4-kb molecule. One type consists of at least two families which are highly reiterated and are not confined to the Y chromosome. The other type is composed of an estimated.

Original languageEnglish (US)
Pages (from-to)3343-3353
Number of pages11
JournalBiochemistry
Volume18
Issue number15
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Biochemistry

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