Organ donation and utilization, 1995-2004: Entering the collaborative era

W. H. Marks, D. Wagner, T. C. Pearson, J. P. Orlowski, P. W. Nelson, J. J. McGowan, M. K. Guidinger, J. Burdick

Research output: Contribution to journalReview articlepeer-review

Abstract

Continued progress in organ donation will help enable transplantation to alleviate the increasing incidence of end-stage organ disease. This article discusses the implementation and effect of the federally initiated Organ Donation Breakthrough Collaborative; it then reviews organ donation data, living and deceased, from 1995 to 2004. It is the first annual report of the Scientific Registry of Transplant Recipients to include national data following initiation of the collaborative in 2003. Prior to that, annual growth in deceased donation was 2%-4%; in 2004, after initiation of the collaborative, deceased donation increased 11%. Identification and dissemination of best practices for organ donation have emphasized new strategies for improved consent, including revised approaches to minority participation, timing of requests and team design. The number of organs recovered from donation after cardiac death (DCD) grew from 64 in 1995 to 391 in 2004. While efforts are ongoing to develop methodologies for identifying expanded criteria donors (ECD) for organs other than kidney, it is clear DCD and ECD raise questions regarding cost and recovery. The number of living donor organs increased from 3493 in 1995 to 7002 in 2004; data show trends toward more living unrelated donors and those providing non-directed donations.

Original languageEnglish (US)
Pages (from-to)1101-1110
Number of pages10
JournalAmerican Journal of Transplantation
Volume6
Issue number5 II
DOIs
StatePublished - May 2006
Externally publishedYes

Keywords

  • Deceased donors
  • Donation after cardiac death (DCD)
  • Donation service area (DSA)
  • Expanded criteria donors
  • Living donors
  • Organ Donation Breakthrough Collaborative
  • Organ donation
  • Organ procurement
  • Organ procurement organization (OPO) SRTR

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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