Organ blood flow rates and cardiac output of the BALB/c mouse

Susanne B. Gjedde; Albert Gjeode

doi:10.1016/0300-9629(80)90258-3

Organ blood flow rates and cardiac output of the BALB/c mouse

Susanne B. Gjedde, Albert Gjeode

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

1. 1. The major organ blood flows and cardiac output were determined in the anesthetized BALB/c mouse by means of indicator fractionation of labelled butanol. 2. 2. Cardiac output per unit weight of animal was twice as high as observed for rat and six-fold that of man. 3. 3. Cerebral blood flow per unit weight of organ was twice as high as measured in the rat under similar anesthesia. 4. 4. Other organ blood flows corresponded well to flows measured in larger animals. 5. 5. It was argued that indicator fractionation for periods of time exceeding 10-20 sec in the mouse may be inaccurate.

Original language	English (US)
Pages (from-to)	671-674
Number of pages	4
Journal	Comparative Biochemistry and Physiology -- Part A: Physiology
Volume	67
Issue number	4
DOIs	https://doi.org/10.1016/0300-9629(80)90258-3
State	Published - 1980

ASJC Scopus subject areas

Physiology

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AU - Gjeode, Albert

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N2 - 1. 1. The major organ blood flows and cardiac output were determined in the anesthetized BALB/c mouse by means of indicator fractionation of labelled butanol. 2. 2. Cardiac output per unit weight of animal was twice as high as observed for rat and six-fold that of man. 3. 3. Cerebral blood flow per unit weight of organ was twice as high as measured in the rat under similar anesthesia. 4. 4. Other organ blood flows corresponded well to flows measured in larger animals. 5. 5. It was argued that indicator fractionation for periods of time exceeding 10-20 sec in the mouse may be inaccurate.

AB - 1. 1. The major organ blood flows and cardiac output were determined in the anesthetized BALB/c mouse by means of indicator fractionation of labelled butanol. 2. 2. Cardiac output per unit weight of animal was twice as high as observed for rat and six-fold that of man. 3. 3. Cerebral blood flow per unit weight of organ was twice as high as measured in the rat under similar anesthesia. 4. 4. Other organ blood flows corresponded well to flows measured in larger animals. 5. 5. It was argued that indicator fractionation for periods of time exceeding 10-20 sec in the mouse may be inaccurate.

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