TY - JOUR
T1 - Orbital invasion with prolactinoma
T2 - A clinical review of four patients
AU - Karcioglu, Zeynel A.
AU - Aden, Leslie B.
AU - Cruz, Antonio A.V.
AU - Zaslow, Lynda
AU - Saloom, Russell J.
PY - 2002
Y1 - 2002
N2 - Purpose: To present four patients with invasive prolactin-secreting pituitary adenomas extending in the orbit. Methods: Retrospective, noncomparative case series. Results: In all cases, the tumor was a large, invasive prolactin-secreting adenoma. In three cases, significant permanent vision loss occurred and severe disfigurement resulted; two of these patients died of tumor-related complications. In one case, the tumor responded well to medical treatment, and the orbital symptoms improved significantly. Conclusion: Although it is rare for a pituitary adenoma to invade the orbit, devastating consequences to the integrity of the globe and ocular adnexa may result. Therefore, early recognition and proper treatment of orbital pituitary tumors are of utmost importance to minimize ocular and orbital damage.
AB - Purpose: To present four patients with invasive prolactin-secreting pituitary adenomas extending in the orbit. Methods: Retrospective, noncomparative case series. Results: In all cases, the tumor was a large, invasive prolactin-secreting adenoma. In three cases, significant permanent vision loss occurred and severe disfigurement resulted; two of these patients died of tumor-related complications. In one case, the tumor responded well to medical treatment, and the orbital symptoms improved significantly. Conclusion: Although it is rare for a pituitary adenoma to invade the orbit, devastating consequences to the integrity of the globe and ocular adnexa may result. Therefore, early recognition and proper treatment of orbital pituitary tumors are of utmost importance to minimize ocular and orbital damage.
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U2 - 10.1097/00002341-200201000-00010
DO - 10.1097/00002341-200201000-00010
M3 - Review article
C2 - 11910327
AN - SCOPUS:0036149610
SN - 0740-9303
VL - 18
SP - 64
EP - 71
JO - Ophthalmic plastic and reconstructive surgery
JF - Ophthalmic plastic and reconstructive surgery
IS - 1
ER -