Orbital Disease in Neuro-Ophthalmology

Jessica R. Chang, Anna M. Gruener, Timothy J McCulley

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Many abnormalities of the orbit present with neuro-ophthalmic findings, such as impaired ocular motility or alignment, and sensory changes, including optic neuropathy. Comprehensive coverage of all orbital diseases is beyond the scope of this article. This review focuses on diagnosis and management of the most common and the most vision- or life-threatening orbital conditions as well as more recently discovered entities and points of active controversy. These conditions include orbital trauma, vascular disease, inflammatory and infectious diseases, and neoplasms. Common presenting symptoms and associated neuro-orbital diseases also are summarized.

Original languageEnglish (US)
Pages (from-to)125-144
Number of pages20
JournalNeurologic Clinics
Issue number1
StatePublished - Feb 1 2017


  • Enophthalmos
  • Idiopathic orbital inflammatory syndrome
  • IgG4-related disease
  • Orbit
  • Orbital fracture
  • Thyroid eye disease
  • Traumatic optic neuropathy

ASJC Scopus subject areas

  • Clinical Neurology


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