Orbital and adnexal lymphoma

Mary E. Aronow, Brian T. Hill, Arun D. Singh

Research output: Chapter in Book/Report/Conference proceedingChapter


Orbital and adnexal lymphoma (OAL) includes a heterogeneous group of lymphomas, the majority of which are low-grade, indolent, B cell, non-Hodgkin’s lymphomas (NHLs). By definition, OAL affects structures including the eyelids, conjunctiva, lacrimal apparatus, extraocular muscles, and the orbit. Disease may be limited to a single, localized tumor, or it may be multifocal. Overlap with ocular adnexal sites is common (10–20 % of cases), and coexisting uveal involvement has been observed. Moreover, OAL can affect regional, central, and peripheral lymph nodes as well as other distant extranodal sites. The 10-year, disease-specific mortality is approximately 5–10 %. Many of the advances in understanding OAL were initially demonstrated in systemic lymphoma.

Original languageEnglish (US)
Title of host publicationClinical Ophthalmic Oncology
Subtitle of host publicationOrbital Tumors, Second Edition
PublisherSpringer Berlin Heidelberg
Number of pages17
ISBN (Electronic)9783642404924
ISBN (Print)9783642404917
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Medicine(all)


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