Oral rehydration therapy in well-nourished ambulatory children

M. Santosham, E. Carrera, R. B. Sack

Research output: Contribution to journalArticlepeer-review


Oral rehydration solutions (ORS) containing 90 mmol/liter or 50 mmol/liter of sodium have been successfully used in the treatment of hospitalized well-nourished and undernourished children; however, few data are available on the use of these ORS in well-nourished ambulatory children with minimal dehydration. We therefore compared the safety and efficacy of both ORS with standard outpatient management in a controlled, randomized study among 93 well-nourished children aged 3 months to 2 years, with minimal dehydration secondary to acute diarrhea at an outpatient clinic in Panama. Patients in all three groups were hydrated successfully. However, patients in both ORS groups gained significantly (P < 0.05) more weight at the 2-week follow-up compared to the control group. There were no complications due to the use of either ORS. No child developed hypernatremia nor hyponatremia during therapy. These studies indicate that both ORS (containing 90 or 50 mmol/liter of sodium) are effective and safe in hydrating well-nourished ambulatory children with minimal dehydration.

Original languageEnglish (US)
Pages (from-to)804-808
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number4
StatePublished - 1983

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases


Dive into the research topics of 'Oral rehydration therapy in well-nourished ambulatory children'. Together they form a unique fingerprint.

Cite this