Oral rehydration therapy for treatment of rotavirus diarrhea in a rural treatment center in Bangladesh

P. R. Taylor, M. H. Merson, R. E. Black, A. S. Mizanur Rahman, M. D. Yunus, A. R. Alim, R. H. Yolken

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Abstract

In November 1977, an enzyme-linked immunosorbent assay for detecting rotavirus antigen was introduced in the laboratory of a rural treatment center in Bangladesh. During the next 40 days rotavirus without other pathogens was found in the stools of 216 (45%) of 480 children under age 5 yr who visited the center with a gastrointestinal illness. One hundred and eighty-eight (87%) of these children were treated with oral rehydration alone, using the solution currently recommended by the World Health Organization, while 28 (13%) also required some intravenous rehydration; there were no deaths. Oral rehydration treatment was judged successful in 205 (95%) of the rotavirus patients and was not associated with any serious side effects. Oral rehydration treatment, with this solution, has been used extensively and successfully in the treatment of enterotoxin-mediated diarrhea and can also safely be used for treating rotavirus diarrhea in infants and young children.

Original languageEnglish (US)
Pages (from-to)376-379
Number of pages4
JournalArchives of disease in childhood
Volume55
Issue number5
DOIs
StatePublished - Jan 1 1980
Externally publishedYes

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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