Oral rehydration therapy for treatment of rotavirus diarrhea in a rural treatment center in Bangladesh

P. R. Taylor, M. H. Merson, Robert E Black, A. S. Mizanur Rahman, M. D. Yunus, A. R. Alim, Robert H Yolken

Research output: Contribution to journalArticle

Abstract

In November 1977, an enzyme-linked immunosorbent assay for detecting rotavirus antigen was introduced in the laboratory of a rural treatment center in Bangladesh. During the next 40 days rotavirus without other pathogens was found in the stools of 216 (45%) of 480 children under age 5 yr who visited the center with a gastrointestinal illness. One hundred and eighty-eight (87%) of these children were treated with oral rehydration alone, using the solution currently recommended by the World Health Organization, while 28 (13%) also required some intravenous rehydration; there were no deaths. Oral rehydration treatment was judged successful in 205 (95%) of the rotavirus patients and was not associated with any serious side effects. Oral rehydration treatment, with this solution, has been used extensively and successfully in the treatment of enterotoxin-mediated diarrhea and can also safely be used for treating rotavirus diarrhea in infants and young children.

Original languageEnglish (US)
Pages (from-to)376-379
Number of pages4
JournalArchives of Disease in Childhood
Volume55
Issue number5
StatePublished - 1980
Externally publishedYes

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Bangladesh
Rotavirus
Fluid Therapy
Diarrhea
Enterotoxins
Therapeutics
Enzyme-Linked Immunosorbent Assay
Antigens

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Oral rehydration therapy for treatment of rotavirus diarrhea in a rural treatment center in Bangladesh. / Taylor, P. R.; Merson, M. H.; Black, Robert E; Mizanur Rahman, A. S.; Yunus, M. D.; Alim, A. R.; Yolken, Robert H.

In: Archives of Disease in Childhood, Vol. 55, No. 5, 1980, p. 376-379.

Research output: Contribution to journalArticle

Taylor, P. R. ; Merson, M. H. ; Black, Robert E ; Mizanur Rahman, A. S. ; Yunus, M. D. ; Alim, A. R. ; Yolken, Robert H. / Oral rehydration therapy for treatment of rotavirus diarrhea in a rural treatment center in Bangladesh. In: Archives of Disease in Childhood. 1980 ; Vol. 55, No. 5. pp. 376-379.
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