Oral immunotherapy for food allergy

Research output: Contribution to journalReview article

Abstract

Food allergy is a potentially life-threatening condition with no approved therapies apart from avoidance and injectable epinephrine for treatment of acute allergic reactions. Oral immunotherapy (OIT) is an experimental treatment in which patients consume gradually increasing quantities of the food to which they are allergic in an attempt to induce some level of desensitization. While desensitization is possible in most patients, OIT carries significant risks for allergic reactions, and the ability to induce longer-term tolerance has not yet been established. This review focuses on selected studies of OIT for the treatment of common food allergies such as cow’s milk, hen’s egg, and peanut.

Original languageEnglish (US)
Pages (from-to)151-159
Number of pages9
JournalJournal of Investigational Allergology and Clinical Immunology
Volume27
Issue number3
DOIs
StatePublished - 2017

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Keywords

  • Cow’s milk
  • Desensitization
  • Food allergy
  • Hen’s egg
  • Immunoglobulin E (IgE)
  • Omalizumab
  • Oral immunotherapy
  • Peanut
  • Skin prick test (SPT)
  • Sustained unresponsiveness
  • Tolerance

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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