Oral and maxillofacial manifestations of familial adenomatous polyposis

M. A. Wijn, J. J. Keller, Francis M Giardiello, H. S. Brand

Research output: Contribution to journalArticle

Abstract

Patients with familial adenomatous polyposis (FAP) develop multiple premalignant colorectal adenomas. Untreated, one or more of these polyps will progress to colorectal carcinoma in middle-aged adults. Extra-intestinal manifestations of FAP are frequently observed and this combination has been called Gardner's syndrome. Oral and maxillofacial symptoms of FAP include an increased risk of jaw osteomas, odontomas and supernumerary or unerupted teeth. Early diagnosis of FAP is crucial and may be life saving. As oral signs usually precede gastrointestinal symptoms, the dentist may play an important role in the diagnosis of FAP.

Original languageEnglish (US)
Pages (from-to)360-365
Number of pages6
JournalOral Diseases
Volume13
Issue number4
DOIs
StatePublished - Jul 2007

Fingerprint

Oral Manifestations
Adenomatous Polyposis Coli
Unerupted Tooth
Odontoma
Gardner Syndrome
Supernumerary Tooth
Osteoma
Polyps
Jaw
Dentists
Adenoma
Early Diagnosis
Colorectal Neoplasms

Keywords

  • APC-gene
  • Colorectal carcinoma
  • Gardner's syndrome
  • Odontoma
  • Osteoma

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Oral and maxillofacial manifestations of familial adenomatous polyposis. / Wijn, M. A.; Keller, J. J.; Giardiello, Francis M; Brand, H. S.

In: Oral Diseases, Vol. 13, No. 4, 07.2007, p. 360-365.

Research output: Contribution to journalArticle

Wijn, M. A. ; Keller, J. J. ; Giardiello, Francis M ; Brand, H. S. / Oral and maxillofacial manifestations of familial adenomatous polyposis. In: Oral Diseases. 2007 ; Vol. 13, No. 4. pp. 360-365.
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