Optimizing Treatment Monitoring in Resource Limited Settings in the Era of Routine Viral Load Monitoring

Castelnuovo Barbara, Steven James Reynolds

Research output: Contribution to journalReview article

Abstract

Purpose of review: Routine viral load monitoring (VLM) for patients on antiretroviral treatment (ART) is being scaled up in resource limited settings. Recent findings: VLM potentially has several roles in improving HIV care and includes identifying patients with treatment failure and in need of second-line ART. VLM can also be used as a tool to improve adherence to ART, with 60% of the patients with detectable viral load achieving suppression following ART adherence counseling. VLM may play a role in optimizing differentiated care strategies, by identifying patients who need more close follow-up and adherence support and those who need minimal support. Finally, by ensuring that patients achieve viral suppression, VLM plays an important role in prevention of transmission to partners and infants. Summary: Early reports indicate that acting on viral load results to facilitate timely switching is still an ongoing challenge with delayed switches still being common.

Original languageEnglish (US)
JournalCurrent Tropical Medicine Reports
Volume4
Issue number1
DOIs
StatePublished - Mar 1 2017

Fingerprint

Viral Load
Therapeutics
Physiologic Monitoring
Treatment Failure
Counseling
HIV

Keywords

  • Coverage
  • HIV care
  • HIV prevention
  • Treatment failure
  • Viral load monitoring

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Cite this

Optimizing Treatment Monitoring in Resource Limited Settings in the Era of Routine Viral Load Monitoring. / Barbara, Castelnuovo; Reynolds, Steven James.

In: Current Tropical Medicine Reports, Vol. 4, No. 1, 01.03.2017.

Research output: Contribution to journalReview article

@article{c79025cfaf954cb885ba225c28f72b3e,
title = "Optimizing Treatment Monitoring in Resource Limited Settings in the Era of Routine Viral Load Monitoring",
abstract = "Purpose of review: Routine viral load monitoring (VLM) for patients on antiretroviral treatment (ART) is being scaled up in resource limited settings. Recent findings: VLM potentially has several roles in improving HIV care and includes identifying patients with treatment failure and in need of second-line ART. VLM can also be used as a tool to improve adherence to ART, with 60{\%} of the patients with detectable viral load achieving suppression following ART adherence counseling. VLM may play a role in optimizing differentiated care strategies, by identifying patients who need more close follow-up and adherence support and those who need minimal support. Finally, by ensuring that patients achieve viral suppression, VLM plays an important role in prevention of transmission to partners and infants. Summary: Early reports indicate that acting on viral load results to facilitate timely switching is still an ongoing challenge with delayed switches still being common.",
keywords = "Coverage, HIV care, HIV prevention, Treatment failure, Viral load monitoring",
author = "Castelnuovo Barbara and Reynolds, {Steven James}",
year = "2017",
month = "3",
day = "1",
doi = "10.1007/s40475-017-0098-2",
language = "English (US)",
volume = "4",
journal = "Current Tropical Medicine Reports",
issn = "2196-3045",
publisher = "Springer International Publishing AG",
number = "1",

}

TY - JOUR

T1 - Optimizing Treatment Monitoring in Resource Limited Settings in the Era of Routine Viral Load Monitoring

AU - Barbara, Castelnuovo

AU - Reynolds, Steven James

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Purpose of review: Routine viral load monitoring (VLM) for patients on antiretroviral treatment (ART) is being scaled up in resource limited settings. Recent findings: VLM potentially has several roles in improving HIV care and includes identifying patients with treatment failure and in need of second-line ART. VLM can also be used as a tool to improve adherence to ART, with 60% of the patients with detectable viral load achieving suppression following ART adherence counseling. VLM may play a role in optimizing differentiated care strategies, by identifying patients who need more close follow-up and adherence support and those who need minimal support. Finally, by ensuring that patients achieve viral suppression, VLM plays an important role in prevention of transmission to partners and infants. Summary: Early reports indicate that acting on viral load results to facilitate timely switching is still an ongoing challenge with delayed switches still being common.

AB - Purpose of review: Routine viral load monitoring (VLM) for patients on antiretroviral treatment (ART) is being scaled up in resource limited settings. Recent findings: VLM potentially has several roles in improving HIV care and includes identifying patients with treatment failure and in need of second-line ART. VLM can also be used as a tool to improve adherence to ART, with 60% of the patients with detectable viral load achieving suppression following ART adherence counseling. VLM may play a role in optimizing differentiated care strategies, by identifying patients who need more close follow-up and adherence support and those who need minimal support. Finally, by ensuring that patients achieve viral suppression, VLM plays an important role in prevention of transmission to partners and infants. Summary: Early reports indicate that acting on viral load results to facilitate timely switching is still an ongoing challenge with delayed switches still being common.

KW - Coverage

KW - HIV care

KW - HIV prevention

KW - Treatment failure

KW - Viral load monitoring

UR - http://www.scopus.com/inward/record.url?scp=85048573502&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85048573502&partnerID=8YFLogxK

U2 - 10.1007/s40475-017-0098-2

DO - 10.1007/s40475-017-0098-2

M3 - Review article

AN - SCOPUS:85048573502

VL - 4

JO - Current Tropical Medicine Reports

JF - Current Tropical Medicine Reports

SN - 2196-3045

IS - 1

ER -