Optimizing the detection of venous invasion in colorectal cancer: The Ontario, Canada, experience and beyond

Heather Dawson, Richard Kirsch, David K. Driman, David E. Messenger, Naziheh Assarzadegan, Robert H. Riddell

Research output: Contribution to journalArticlepeer-review

Abstract

Venous invasion (VI) is a well-established independent prognostic indicator in colorectal cancer (CRC). Its accurate detection is particularly important in stage II CRC as it may influence the decision to administer adjuvant therapy. The Royal College of Pathologists (RCPath) of the United Kingdom state that VI should be detected in at least 30% of CRC resection specimens. However, our experience in Ontario, Canada suggests that this (conservative) benchmark is rarely met. This article highlights the "Ontario experience" with respect to VI reporting and the key role that careful morphologic assessment, elastin staining and knowledge transfer has played in improving VI detection provincially and beyond.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalFrontiers in Oncology
Volume4
Issue numberNOV
DOIs
StatePublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint

Dive into the research topics of 'Optimizing the detection of venous invasion in colorectal cancer: The Ontario, Canada, experience and beyond'. Together they form a unique fingerprint.

Cite this