Optimizing Surgical Treatment for Phyllodes Tumor

Kai Chen, Yanbo Chen, Paul Cartwright, Lisa Jacobs

Research output: Contribution to journalArticle

Abstract

Purpose: This article aims to discuss the optimal surgical treatment for Phyllodes Tumor. A general overview of each grade will be presented along with relevant findings in recent literature. An argument for a modification to current practice standards and guidelines will be introduced as histological grading has become increasingly important. Recent Findings: Based on our literature review, benign phyllodes tumors have a mean local recurrence rate of 6.9% and a mean distant metastasis rate of 0.01%. Recent studies have revealed there is no statistical difference in local recurrence for patients with positive or negative margins following tumor resection of the benign grade. Summary: The National Comprehensive Cancer Network recommends wide local excisions with negative margins of 1 cm for all Phyllodes Tumors. However, we believe these guidelines are obsolete as the histological benign grade has extremely low rates of local recurrence and metastasis. In order to decrease patient morbidity, close surveillance and observation should be considered over standard practice following a positive margin in benign Phyllodes Tumors.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalCurrent Breast Cancer Reports
DOIs
Publication statusAccepted/In press - Mar 19 2018

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Keywords

  • Histology
  • Local recurrence
  • Phyllodes tumor
  • Radiation therapy
  • Surgical margin

ASJC Scopus subject areas

  • Oncology

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