Optimizing sensitivity-resolution trade-off using generalized detection/discrimination task and three-class ROC analysis

Lana Volokh, Xin He, Eric C. Frey, B. M.W. Tsui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The goal of this work is to address the problem of quantifying sensitivity/resolution trade-off in emission imaging system optimization. We propose a task and a figure of merit (FOM) based on 3-class ROC analysis. The task combines detection of a lesion on a variable background with discrimination of a lesion from an adjacent structure, modeled by Rayleigh task. Recently developed practical framework for conducting 3-class ROC analysis is utilized to evaluate the performance of channelized hotelling observer. A primitive imaging system model is used to investigate effects of resolution, sensitivity and imaging time. Volume under ROC surface (VUS) is used as the primary FOM in assessment of the task performance. The FOM is optimal according to several decision strategies. We present results of initial tests of the model properties in a simplified planar imaging setting. We observe that system resolution requirements are critical for observer performance in the proposed task. Initial experience shows that the new approach provides useful insight into factors affecting observer performance in realistic experimental designs.

Original languageEnglish (US)
Title of host publication2006 IEEE Nuclear Science Symposium - Conference Record
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1692-1695
Number of pages4
ISBN (Print)1424405610, 9781424405619
DOIs
StatePublished - Jan 1 2006
Event2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD - San Diego, CA, United States
Duration: Oct 29 2006Nov 4 2006

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume3
ISSN (Print)1095-7863

Other

Other2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
CountryUnited States
CitySan Diego, CA
Period10/29/0611/4/06

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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    Volokh, L., He, X., Frey, E. C., & Tsui, B. M. W. (2006). Optimizing sensitivity-resolution trade-off using generalized detection/discrimination task and three-class ROC analysis. In 2006 IEEE Nuclear Science Symposium - Conference Record (pp. 1692-1695). [4179337] (IEEE Nuclear Science Symposium Conference Record; Vol. 3). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2006.354224