Optimization of plasmepsin inhibitor by focusing on similar structural feature with chloroquine to avoid drug-resistant mechanism of Plasmodium falciparum

Takuya Miura, Koushi Hidaka, Yukiko Azai, Keisuke Kashimoto, Yuko Kawasaki, Shen En Chen, Renato Ferreira De Freitas, Ernesto Freire, Yoshiaki Kiso

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Medicine & Life Sciences

Chemical Compounds