Optimization of energy window and evaluation of scatter compensation methods in MPS using the ideal observer with model mismatch

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work, we used the ideal observer (IO) and IO with model mismatch (IO-MM) applied in the projection domain and an anthropomorphic Channelized Hotelling Observer (CHO) applied to reconstructed images to optimize the acquisition energy window width and evaluate various scatter compensation methods in the context of a myocardial perfusion SPECT defect detection task. The IO has perfect knowledge of the image formation process and thus reflects performance with perfect compensation for image-degrading factors. Thus, using the IO to optimize imaging systems could lead to suboptimal parameters compared to those optimized for humans interpreting SPECT images reconstructed with imperfect or no compensation. The IO-MM allows incorporating imperfect system models into the IO optimization process. We found that with near-perfect scatter compensation, the optimal energy window for the IO and CHO were similar; in its absence the IO-MM gave a better prediction of the optimal energy window for the CHO using different scatter compensation methods. These data suggest that the IO-MM may be useful for projection-domain optimization when model mismatch is significant, and that the IO is useful when followed by reconstruction with good models of the image formation process.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment
PublisherSPIE
Volume9416
ISBN (Print)9781628415063
DOIs
StatePublished - 2015
EventMedical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment - Orlando, United States
Duration: Feb 25 2015Feb 26 2015

Other

OtherMedical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment
CountryUnited States
CityOrlando
Period2/25/152/26/15

Fingerprint

Single-Photon Emission-Computed Tomography
optimization
evaluation
Perfusion
Image processing
projection
energy
Imaging systems
acquisition
Compensation and Redress
defects
predictions

Keywords

  • anthropomorphic observer
  • model mismatch
  • scatter compensation and SPECT
  • The ideal observer

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Optimization of energy window and evaluation of scatter compensation methods in MPS using the ideal observer with model mismatch. / Ghaly, Mickel; Links, Jonathan M; Frey, Eric.

Medical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment. Vol. 9416 SPIE, 2015. 94160N.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ghaly, M, Links, JM & Frey, E 2015, Optimization of energy window and evaluation of scatter compensation methods in MPS using the ideal observer with model mismatch. in Medical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment. vol. 9416, 94160N, SPIE, Medical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment, Orlando, United States, 2/25/15. https://doi.org/10.1117/12.2081043
Ghaly M, Links JM, Frey E. Optimization of energy window and evaluation of scatter compensation methods in MPS using the ideal observer with model mismatch. In Medical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment. Vol. 9416. SPIE. 2015. 94160N https://doi.org/10.1117/12.2081043
Ghaly, Mickel ; Links, Jonathan M ; Frey, Eric. / Optimization of energy window and evaluation of scatter compensation methods in MPS using the ideal observer with model mismatch. Medical Imaging 2015: Image Perception, Observer Performance, and Technology Assessment. Vol. 9416 SPIE, 2015.
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