@inproceedings{d8dc05386d5e42acb9bcc71b5ec9335f,
title = "Optical stimulation of the cavernous nerves in the rat prostate",
abstract = "Laser nerve stimulation has recently been studied as an alternative to electrical stimulation in neuroscience. Advantages include non-contact stimulation, improved spatial selectivity, and elimination of electrical stimulation artifacts. This study explores laser stimulation of the rat cavernous nerves, as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy. The cavernous nerves were surgically exposed in a total of 10 male rats. A Thulium fiber laser stimulated the nerves, with a wavelength of 1870 nm, pulse energy of 7.5 mJ, radiant exposure of 1 J/cm2, pulse duration of 2.5 ms, pulse rate of 10 Hz, and 1-mm laser spot diameter, for a stimulation time of 60 s. A significant increase in the intracavernosal pressure was detected upon laser stimulation, with pressure returning to baseline levels after stimulation. This study demonstrates the feasibility of non-contact laser stimulation of the cavernous nerves using near-infrared laser radiation.",
keywords = "Cavernous, Fiber, Laser, Nerve, Neurovascular, Prostatectomy, Stimulation, Thulium",
author = "Fried, {Nathaniel M.} and Lagoda, {Gwen A.} and Scott, {Nicholas J.} and Su, {Li Ming} and Burnett, {Arthur L.}",
year = "2008",
doi = "10.1117/12.760950",
language = "English (US)",
isbn = "9780819470171",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
note = "Photonic Therapeutics and Diagnostics IV ; Conference date: 19-01-2008 Through 19-01-2008",
}