Optical coherence tomography vs. high-frequency ultrasound during noninvasive laser Coagulation of the canine vas deferens

Christopher M. Cilip, Mohamad E. Allaf, Nathaniel M. Fried

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A noninvasive approach to vasectomy may eliminate male fear of complications related to surgery and increase its acceptance. Noninvasive laser thermal occlusion of the canine vas deferens has recently been reported. In this study, optical coherence tomography (OCT) and high-frequency ultrasound (HFUS) are compared for monitoring laser thermal coagulation of the vas in an acute canine model. Bilateral noninvasive laser coagulation of the vas was performed in 6 dogs (n=12 vasa) using a Ytterbium fiber laser wavelength of 1075 nm, incident power of 9.0 W, pulse duration of 500 ms, pulse rate of 1 Hz, and 3-mm-diameter spot. Cryogen spray cooling was used to prevent skin burns during the procedure. An OCT system with endoscopic probe and a HFUS system with 20-MHz transducer were used to image the vas immediately before and after the procedure. Vasa were then excised and processed for gross and histologic analysis for comparison with OCT and HFUS images. OCT provided highresolution, superficial imaging of the compressed vas within the vas ring clamp, while HFUS provided deeper imaging of the vas held manually in the scrotal fold. Both OCT and high HFUS are promising imaging modalities for real-time confirmation of vas occlusion during noninvasive laser vasectomy.

Original languageEnglish (US)
Title of host publicationPhotonic Therapeutics and Diagnostics VIII
DOIs
StatePublished - May 14 2012
EventPhotonic Therapeutics and Diagnostics VIII - San Francisco, CA, United States
Duration: Jan 21 2012Jan 24 2012

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8207
ISSN (Print)1605-7422

Other

OtherPhotonic Therapeutics and Diagnostics VIII
CountryUnited States
CitySan Francisco, CA
Period1/21/121/24/12

Keywords

  • Laser
  • Male sterilization
  • Noninvasive
  • Optical coherence tomography
  • Ultrasound
  • Vasectomy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Cilip, C. M., Allaf, M. E., & Fried, N. M. (2012). Optical coherence tomography vs. high-frequency ultrasound during noninvasive laser Coagulation of the canine vas deferens. In Photonic Therapeutics and Diagnostics VIII [820715] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8207). https://doi.org/10.1117/12.905259