Optical coherence tomography enhanced depth imaging of chorioretinal folds in patients with orbital tumors

Zhi Yu Peng, Lu Gan, Kang Xue, Akrit Sodhi, Xiao Feng Ye, Hui Ren, Jiang Qian

Research output: Contribution to journalArticlepeer-review


• AIM: To characterize spectral-domain optical coherence tomography (SD-OCT) features of chorioretinal folds in orbital mass imaged using enhanced depth imaging (EDI). • METHODS: Prospective observational case-control study was conducted in 20 eyes of 20 patients, the uninvolved eye served as a control. All the patients underwent clinical fundus photography, computed tomography, EDI SD-OCT imaging before and after surgery. Two patients with cavernous hemangiomas underwent intratumoral injection of bleomycin A5; the remaining patients underwent tumor excision. Patients were followed 1 to 14mo following surgery (average follow up, 5.8mo). • RESULTS: Visual acuity prior to surgery ranged from 20/20 to 20/200. Following surgery, 5 patients’ visual acuity remained unchanged while the remaining 15 patients had a mean letter improvement of 10 (range 4 to 26 letters). Photoreceptor inner/outer segment defects were found in 10 of 15 patients prior to surgery. Following surgical excision, photoreceptor inner/outer segment defects fully resolved in 8 of these 10 patients. • CONCLUSION: Persistence of photoreceptor inner/ outer segment defects caused by compression of the globe by an orbital mass can be associated with reduced visual prognosis. Our findings suggest that photoreceptor inner/ outer segment defects on EDI SD-OCT could be an indicator for immediate surgical excision of an orbital mass causing choroidal compression.

Original languageEnglish (US)
Pages (from-to)233-237
Number of pages5
JournalInternational Journal of Ophthalmology
Issue number2
StatePublished - Feb 18 2023


  • chorioretinal folds
  • choroidal thickness
  • enhanced depth imaging optical coherence tomography
  • inner/outer segment defects
  • orbital mass

ASJC Scopus subject areas

  • Ophthalmology


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