Optical coherence tomography angiography imaging in inherited retinal diseases

Sally S. Ong; Tapan P. Patel; Mandeep S. Singh

doi:10.3390/jcm8122078

Optical coherence tomography angiography imaging in inherited retinal diseases

Sally S. Ong, Tapan P. Patel, Mandeep S. Singh

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.

Original language	English (US)
Article number	2078
Journal	Journal of Clinical Medicine
Volume	8
Issue number	12
DOIs	https://doi.org/10.3390/jcm8122078
State	Published - 2019

Keywords

Best disease
Choriocapillaris
Choroideremia
Degenerative retinal diseases
Gene therapy
In vivo imaging
Optical coherence tomography angiography
Retinal pigment epithelium
Retinitis pigmentosa
Stargardt disease

ASJC Scopus subject areas

General Medicine

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10.3390/jcm8122078

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title = "Optical coherence tomography angiography imaging in inherited retinal diseases",

abstract = "Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.",

keywords = "Best disease, Choriocapillaris, Choroideremia, Degenerative retinal diseases, Gene therapy, In vivo imaging, Optical coherence tomography angiography, Retinal pigment epithelium, Retinitis pigmentosa, Stargardt disease",

author = "Ong, {Sally S.} and Patel, {Tapan P.} and Singh, {Mandeep S.}",

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language = "English (US)",

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journal = "Journal of Clinical Medicine",

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AU - Ong, Sally S.

AU - Patel, Tapan P.

AU - Singh, Mandeep S.

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N2 - Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.

AB - Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.

KW - Best disease

KW - Choriocapillaris

KW - Choroideremia

KW - Degenerative retinal diseases

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KW - Optical coherence tomography angiography

KW - Retinal pigment epithelium

KW - Retinitis pigmentosa

KW - Stargardt disease

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Optical coherence tomography angiography imaging in inherited retinal diseases

Abstract

Keywords

ASJC Scopus subject areas

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