Optical Coherence Tomography Angiography and en Face Optical Coherence Tomography Features of Paracentral Acute Middle Maculopathy

Jayanth Sridhar, Abtin Shahlaee, Ehsan Rahimy, Bryan K. Hong, M. Ali Khan, Joseph I. Maguire, James P. Dunn, Sonia Mehta, Allen C. Ho

Research output: Contribution to journalArticle

Abstract

Purpose To characterize the optical coherence tomography (OCT) angiography, en face OCT, and microperimetry features of paracentral acute middle maculopathy in both the acute phase and after resolution, and to propose a classification of distinct subtypes of this entity. Design Retrospective observational case series. Methods Clinical histories, high-resolution digital color imaging, spectral-domain OCT images, fluorescein angiography, OCT angiography images, and en face OCT images of 16 patients with paracentral acute middle maculopathy were evaluated. Microperimetry was available in 6 patients. Results The most common referring diagnoses were isolated branch retinal arterial occlusion (5/16), combined central retinal vein and cilioretinal artery occlusion (4/16), and isolated central retinal vein occlusion (4/16). All patients demonstrated hyperreflective plaque-like lesions at the level of the inner nuclear layer on spectral-domain OCT, with no fluorescein angiographic correlate. OCT angiography demonstrated variable areas of capillary dropout within the superficial and deep retinal capillary plexi in these areas. En face OCT highlighted confluent areas of middle retina hyperreflectivity corresponding to these lesions. Three distinct en face OCT patterns were observed: arteriolar, fern-like, and globular. Microperimetry demonstrated relative scotomas mapping to the area of middle retinal hyperreflectivity seen on en face OCT. Conclusions Paracentral acute middle maculopathy may be best evaluated with the use of en face OCT imaging, which corresponds to subjective and objective visual field defects. En face OCT appearance may be used to classify paracentral acute maculopathy into distinct subtypes.

Original languageEnglish (US)
Pages (from-to)1259-1268e2
JournalAmerican Journal of Ophthalmology
Volume160
Issue number6
DOIs
StatePublished - 2015
Externally publishedYes

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Optical Coherence Tomography
Angiography
Retinal Vein
Ferns
Scotoma
Retinal Vein Occlusion
Fluorescein Angiography
Visual Fields
Fluorescein
Retina
Arteries
Color

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

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Optical Coherence Tomography Angiography and en Face Optical Coherence Tomography Features of Paracentral Acute Middle Maculopathy. / Sridhar, Jayanth; Shahlaee, Abtin; Rahimy, Ehsan; Hong, Bryan K.; Khan, M. Ali; Maguire, Joseph I.; Dunn, James P.; Mehta, Sonia; Ho, Allen C.

In: American Journal of Ophthalmology, Vol. 160, No. 6, 2015, p. 1259-1268e2.

Research output: Contribution to journalArticle

Sridhar, J, Shahlaee, A, Rahimy, E, Hong, BK, Khan, MA, Maguire, JI, Dunn, JP, Mehta, S & Ho, AC 2015, 'Optical Coherence Tomography Angiography and en Face Optical Coherence Tomography Features of Paracentral Acute Middle Maculopathy', American Journal of Ophthalmology, vol. 160, no. 6, pp. 1259-1268e2. https://doi.org/10.1016/j.ajo.2015.09.016
Sridhar, Jayanth ; Shahlaee, Abtin ; Rahimy, Ehsan ; Hong, Bryan K. ; Khan, M. Ali ; Maguire, Joseph I. ; Dunn, James P. ; Mehta, Sonia ; Ho, Allen C. / Optical Coherence Tomography Angiography and en Face Optical Coherence Tomography Features of Paracentral Acute Middle Maculopathy. In: American Journal of Ophthalmology. 2015 ; Vol. 160, No. 6. pp. 1259-1268e2.
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