Optic Neuropathy in Systemic Lupus Erythematosus

Douglas A. Jabs, Neil R. Miller, Steven A. Newman, Mary A. Johnson, Mary Betty Stevens

Research output: Contribution to journalArticlepeer-review


We report data from seven cases of optic neuropathy in systemic lupus erythematosus. The visual outcome varied, but improvement occasionally occurred following treatment with corticosteroids. The clinical picture was variable and could present as acute retrobulbar optic neuritis, ischemic optic neuropathy, or slowly progressive visual loss. Visual evoked response testing revealed increased latency in two patients and loss of amplitude in two others; a fifth patient had both findings in the involved eye. Despite the variable presentation, the probable pathogenesis in all cases is vaso-occlusive disease in small vessels of the optic nerves.

Original languageEnglish (US)
Pages (from-to)564-568
Number of pages5
JournalArchives of ophthalmology
Issue number4
StatePublished - Apr 1986

ASJC Scopus subject areas

  • Ophthalmology


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