Optic nerve head swelling and optic atrophy in the systemic mucopolysaccharidoses

M. L Z Collins, E. I. Traboulsi, I. H. Maumenee

Research output: Contribution to journalArticle

Abstract

The ocular findings in 108 patients representative of all types of mucopolysaccharidoses (MPS) were reviewed. Attention was focused on optic nerve head appearance. Optic nerve head swelling was observed in 8/14 eyes of MPS I-Hurler (MPS I-H); 9/21 MPS I-Hurler-Scheie (MPS I-H-S); 0/4 MPS I-S; 13/66 MPS II;1/22 MPS III; 0/58 MPS IV; 5/12 MPS VI; and 2/2 MPS VII eyes. In three patients, optic nerve head swelling was present in one eye and optic atrophy in the fellow eye; in four patients, optic atrophy followed disc elevation; three patients presented with bilateral optic atrophy. It was concluded that optic nerve head swelling precedes the development of optic atrophy in the systemic MPS.

Original languageEnglish (US)
Pages (from-to)1445-1449
Number of pages5
JournalOphthalmology
Volume97
Issue number11
StatePublished - 1990

Fingerprint

Mucopolysaccharidoses
Mucopolysaccharidosis I
Optic Atrophy
Optic Disk
Mucopolysaccharidosis II
Mucopolysaccharidosis VII
Mucopolysaccharidosis VI
Mucopolysaccharidosis III
Mucopolysaccharidosis IV
Patient Advocacy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Collins, M. L. Z., Traboulsi, E. I., & Maumenee, I. H. (1990). Optic nerve head swelling and optic atrophy in the systemic mucopolysaccharidoses. Ophthalmology, 97(11), 1445-1449.

Optic nerve head swelling and optic atrophy in the systemic mucopolysaccharidoses. / Collins, M. L Z; Traboulsi, E. I.; Maumenee, I. H.

In: Ophthalmology, Vol. 97, No. 11, 1990, p. 1445-1449.

Research output: Contribution to journalArticle

Collins, MLZ, Traboulsi, EI & Maumenee, IH 1990, 'Optic nerve head swelling and optic atrophy in the systemic mucopolysaccharidoses', Ophthalmology, vol. 97, no. 11, pp. 1445-1449.
Collins MLZ, Traboulsi EI, Maumenee IH. Optic nerve head swelling and optic atrophy in the systemic mucopolysaccharidoses. Ophthalmology. 1990;97(11):1445-1449.
Collins, M. L Z ; Traboulsi, E. I. ; Maumenee, I. H. / Optic nerve head swelling and optic atrophy in the systemic mucopolysaccharidoses. In: Ophthalmology. 1990 ; Vol. 97, No. 11. pp. 1445-1449.
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