Opiate receptor: Demonstration in nervous tissue

Candace B. Pert, Solomon H. Snyder

Research output: Contribution to journalArticle

Abstract

Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig intestine. Competition for the opiate receptor by various opiates and their antagonists closely parallels their pharmacological potency. The opiate receptor is confined to nervous tissue.

Original languageEnglish (US)
Pages (from-to)1007-1009
Number of pages3
JournalScience
Volume179
Issue number4077
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • General

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