Ophthalmoplegia and Dissociated Nystagmus in Abetalipoproteinemia

Robert D. Yee, David G. Cogan, David S. Zee

Research output: Contribution to journalArticlepeer-review


A characteristic pattern of acquired exotropia, progressive paresis of the medial rectus muscles, and dissociated nystagmus on lateral gaze was found in three patients with abetalipoproteinemia. Study with electronystagmography of the eye movements of one patient revealed abnormally slow voluntary saccades and slow or absent fast components of vestibular nystagmus, optokinetic nystagmus, and jerk-type, dissociated nystagmus. Defects in central nervous system centers generating saccadic eye movements are postulated.

Original languageEnglish (US)
Pages (from-to)571-575
Number of pages5
JournalArchives of ophthalmology
Issue number4
StatePublished - Apr 1976
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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