Oocyte maturation failure: A syndrome of bad eggs

Stephanie Beall, Carol Brenner, James Segars

Research output: Contribution to journalArticle

Abstract

To show that disruption of meiotic competence results in cell cycle arrest, and the production of immature oocytes that are not capable of fertilization. Through an extensive review of animal studies and clinical case reports, we define the syndrome of oocyte maturation failure as a distinct oocyte disorder, present a classification system based on clinical parameters, and discuss the potential molecular origins for the disease.

Original languageEnglish (US)
Pages (from-to)2507-2513
Number of pages7
JournalFertility and Sterility
Volume94
Issue number7
DOIs
StatePublished - Dec 2010
Externally publishedYes

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Oocytes
Cell Cycle Checkpoints
Fertilization
Mental Competency
Clinical Studies

Keywords

  • meiotic arrest
  • oocyte arrest
  • Oocyte maturation
  • sterility

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Oocyte maturation failure : A syndrome of bad eggs. / Beall, Stephanie; Brenner, Carol; Segars, James.

In: Fertility and Sterility, Vol. 94, No. 7, 12.2010, p. 2507-2513.

Research output: Contribution to journalArticle

Beall, Stephanie ; Brenner, Carol ; Segars, James. / Oocyte maturation failure : A syndrome of bad eggs. In: Fertility and Sterility. 2010 ; Vol. 94, No. 7. pp. 2507-2513.
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