One-year clinical follow-up with the serpentine balloon expandable stent: Report of the first 100 patients

Ariel Roguin, Luis Gruberg, Walter Markiewicz, Ehud Grenadier, Benjamin Peled, Jamal Hir, Shai Linn, Iris Eisen, Rafael Beyar

Research output: Contribution to journalArticle

Abstract

Background. We recently reported a high technical and 30-day clinical success rate among the first 100 patients treated with the tubular, serpentine design, stainless steel, balloon-expandable stent (beStent(TM)) in Israel. The present study examined the clinical results in these patients after the first year. Methods. Seventy-eight men and 22 women were included in the study. Previous myocardial infarction, bypass surgery and percutaneous transluminal coronary angioplasty had occurred in 52%, 12% and 26% of the patients, respectively. Diabetes mellitus was present in 30 patients and hypertension in 34 patients. One hundred and forty-eight stents of 15, 25, and 35 mm lengths were used. The indications for stenting were suboptimal results (n = 85), bailout conditions (n = 10) or for the prevention of restenosis (n = 8), and lesion types were A (n = 10), B1 (n = 29), B2 (n = 20), and C (n = 44). All patients were clinically monitored with regular visits at 1, 3, 6, 9 and 12 months. Results. Overall, the 12-month event-free survival rate was 82%. Subacute thrombosis occurred in two patients. There were two non-cardiac deaths, one a-wave myocardial infarction, six elective bypass surgeries and 12 target lesion revascularizations. Event-free survival was significantly higher for those with lesions shorter than 15 mm than for those with lesions longer than 15 mm (90% versus 67%, P = 0.003), and for women compared with men (96% versus 78%, P = 0.02). Conclusions. The initial experience with the beStent shows favorable long-term results with an overall event rate of 18% for this subset of relatively complex lesions; higher event rates were observed for longer lesions.

Original languageEnglish (US)
Pages (from-to)421-425
Number of pages5
JournalCoronary Artery Disease
Volume10
Issue number6
StatePublished - 1999
Externally publishedYes

Fingerprint

Stents
Disease-Free Survival
Myocardial Infarction
Coronary Balloon Angioplasty
Stainless Steel
Israel
Diabetes Mellitus
Thrombosis
Survival Rate
Hypertension

Keywords

  • Coronary artery disease
  • Restenosis
  • Stents
  • Transluminal angioplasty

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Roguin, A., Gruberg, L., Markiewicz, W., Grenadier, E., Peled, B., Hir, J., ... Beyar, R. (1999). One-year clinical follow-up with the serpentine balloon expandable stent: Report of the first 100 patients. Coronary Artery Disease, 10(6), 421-425.

One-year clinical follow-up with the serpentine balloon expandable stent : Report of the first 100 patients. / Roguin, Ariel; Gruberg, Luis; Markiewicz, Walter; Grenadier, Ehud; Peled, Benjamin; Hir, Jamal; Linn, Shai; Eisen, Iris; Beyar, Rafael.

In: Coronary Artery Disease, Vol. 10, No. 6, 1999, p. 421-425.

Research output: Contribution to journalArticle

Roguin, A, Gruberg, L, Markiewicz, W, Grenadier, E, Peled, B, Hir, J, Linn, S, Eisen, I & Beyar, R 1999, 'One-year clinical follow-up with the serpentine balloon expandable stent: Report of the first 100 patients', Coronary Artery Disease, vol. 10, no. 6, pp. 421-425.
Roguin A, Gruberg L, Markiewicz W, Grenadier E, Peled B, Hir J et al. One-year clinical follow-up with the serpentine balloon expandable stent: Report of the first 100 patients. Coronary Artery Disease. 1999;10(6):421-425.
Roguin, Ariel ; Gruberg, Luis ; Markiewicz, Walter ; Grenadier, Ehud ; Peled, Benjamin ; Hir, Jamal ; Linn, Shai ; Eisen, Iris ; Beyar, Rafael. / One-year clinical follow-up with the serpentine balloon expandable stent : Report of the first 100 patients. In: Coronary Artery Disease. 1999 ; Vol. 10, No. 6. pp. 421-425.
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abstract = "Background. We recently reported a high technical and 30-day clinical success rate among the first 100 patients treated with the tubular, serpentine design, stainless steel, balloon-expandable stent (beStent(TM)) in Israel. The present study examined the clinical results in these patients after the first year. Methods. Seventy-eight men and 22 women were included in the study. Previous myocardial infarction, bypass surgery and percutaneous transluminal coronary angioplasty had occurred in 52{\%}, 12{\%} and 26{\%} of the patients, respectively. Diabetes mellitus was present in 30 patients and hypertension in 34 patients. One hundred and forty-eight stents of 15, 25, and 35 mm lengths were used. The indications for stenting were suboptimal results (n = 85), bailout conditions (n = 10) or for the prevention of restenosis (n = 8), and lesion types were A (n = 10), B1 (n = 29), B2 (n = 20), and C (n = 44). All patients were clinically monitored with regular visits at 1, 3, 6, 9 and 12 months. Results. Overall, the 12-month event-free survival rate was 82{\%}. Subacute thrombosis occurred in two patients. There were two non-cardiac deaths, one a-wave myocardial infarction, six elective bypass surgeries and 12 target lesion revascularizations. Event-free survival was significantly higher for those with lesions shorter than 15 mm than for those with lesions longer than 15 mm (90{\%} versus 67{\%}, P = 0.003), and for women compared with men (96{\%} versus 78{\%}, P = 0.02). Conclusions. The initial experience with the beStent shows favorable long-term results with an overall event rate of 18{\%} for this subset of relatively complex lesions; higher event rates were observed for longer lesions.",
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T1 - One-year clinical follow-up with the serpentine balloon expandable stent

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AU - Roguin, Ariel

AU - Gruberg, Luis

AU - Markiewicz, Walter

AU - Grenadier, Ehud

AU - Peled, Benjamin

AU - Hir, Jamal

AU - Linn, Shai

AU - Eisen, Iris

AU - Beyar, Rafael

PY - 1999

Y1 - 1999

N2 - Background. We recently reported a high technical and 30-day clinical success rate among the first 100 patients treated with the tubular, serpentine design, stainless steel, balloon-expandable stent (beStent(TM)) in Israel. The present study examined the clinical results in these patients after the first year. Methods. Seventy-eight men and 22 women were included in the study. Previous myocardial infarction, bypass surgery and percutaneous transluminal coronary angioplasty had occurred in 52%, 12% and 26% of the patients, respectively. Diabetes mellitus was present in 30 patients and hypertension in 34 patients. One hundred and forty-eight stents of 15, 25, and 35 mm lengths were used. The indications for stenting were suboptimal results (n = 85), bailout conditions (n = 10) or for the prevention of restenosis (n = 8), and lesion types were A (n = 10), B1 (n = 29), B2 (n = 20), and C (n = 44). All patients were clinically monitored with regular visits at 1, 3, 6, 9 and 12 months. Results. Overall, the 12-month event-free survival rate was 82%. Subacute thrombosis occurred in two patients. There were two non-cardiac deaths, one a-wave myocardial infarction, six elective bypass surgeries and 12 target lesion revascularizations. Event-free survival was significantly higher for those with lesions shorter than 15 mm than for those with lesions longer than 15 mm (90% versus 67%, P = 0.003), and for women compared with men (96% versus 78%, P = 0.02). Conclusions. The initial experience with the beStent shows favorable long-term results with an overall event rate of 18% for this subset of relatively complex lesions; higher event rates were observed for longer lesions.

AB - Background. We recently reported a high technical and 30-day clinical success rate among the first 100 patients treated with the tubular, serpentine design, stainless steel, balloon-expandable stent (beStent(TM)) in Israel. The present study examined the clinical results in these patients after the first year. Methods. Seventy-eight men and 22 women were included in the study. Previous myocardial infarction, bypass surgery and percutaneous transluminal coronary angioplasty had occurred in 52%, 12% and 26% of the patients, respectively. Diabetes mellitus was present in 30 patients and hypertension in 34 patients. One hundred and forty-eight stents of 15, 25, and 35 mm lengths were used. The indications for stenting were suboptimal results (n = 85), bailout conditions (n = 10) or for the prevention of restenosis (n = 8), and lesion types were A (n = 10), B1 (n = 29), B2 (n = 20), and C (n = 44). All patients were clinically monitored with regular visits at 1, 3, 6, 9 and 12 months. Results. Overall, the 12-month event-free survival rate was 82%. Subacute thrombosis occurred in two patients. There were two non-cardiac deaths, one a-wave myocardial infarction, six elective bypass surgeries and 12 target lesion revascularizations. Event-free survival was significantly higher for those with lesions shorter than 15 mm than for those with lesions longer than 15 mm (90% versus 67%, P = 0.003), and for women compared with men (96% versus 78%, P = 0.02). Conclusions. The initial experience with the beStent shows favorable long-term results with an overall event rate of 18% for this subset of relatively complex lesions; higher event rates were observed for longer lesions.

KW - Coronary artery disease

KW - Restenosis

KW - Stents

KW - Transluminal angioplasty

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