One-Hybrid Screens at the Saccharomyces cerevisiae HMR Locus Identify Novel Transcriptional Silencing Factors

Erik D. Andrulis, David C. Zappulla, Krassimira Alexieva-Botcheva, Carlos Evangelista, Rolf Sternglanz

Research output: Contribution to journalArticlepeer-review

Abstract

In Saccharomyces cerevisiae, genes located at the telomeres and the HM loci are subject to transcriptional silencing. Here, we report results of screening a Gal4 DNA-binding domain hybrid library for proteins that cause silencing when targeted to a silencer-defective HMR locus.

Original languageEnglish (US)
Pages (from-to)631-635
Number of pages5
JournalGenetics
Volume166
Issue number1
DOIs
StatePublished - Jan 2004
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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