Onchocerciasis in Malawi. 1. Prevalence, intensity and geographical distribution of Onchocerca volvulus infection in the Thyolo highlands

Research output: Contribution to journalArticle

Abstract

Skin snips from 23 373 persons living in the Thyolo (formerly Cholp) highlands focus of southern Malawi showed infection with Onchocerca volvulus to be unevenly distributed within the highland area. In the centre of the focus most adults were infected, though intensity of infection was light, not exceeding a geometric mean of 8 microfilariae per mg of skin. It was estimated that 327 000 persons live in areas where prevalence of infection exceeds 10% and, of these, 94 500 persons over the age of one year are infected with O. volvulus. There is a significant relationship between infection with O. volvulus and bilateral blindness in the Thyolo focus, although the number of persons blind from onchocerciasis is probably less than 300.

Original languageEnglish (US)
Pages (from-to)493-496
Number of pages4
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume85
Issue number4
DOIs
StatePublished - 1991
Externally publishedYes

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Onchocerca volvulus
Onchocerciasis
Malawi
Infection
Visually Impaired Persons
Microfilariae
Skin
Blindness
Light

ASJC Scopus subject areas

  • Parasitology
  • Medicine(all)

Cite this

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title = "Onchocerciasis in Malawi. 1. Prevalence, intensity and geographical distribution of Onchocerca volvulus infection in the Thyolo highlands",
abstract = "Skin snips from 23 373 persons living in the Thyolo (formerly Cholp) highlands focus of southern Malawi showed infection with Onchocerca volvulus to be unevenly distributed within the highland area. In the centre of the focus most adults were infected, though intensity of infection was light, not exceeding a geometric mean of 8 microfilariae per mg of skin. It was estimated that 327 000 persons live in areas where prevalence of infection exceeds 10{\%} and, of these, 94 500 persons over the age of one year are infected with O. volvulus. There is a significant relationship between infection with O. volvulus and bilateral blindness in the Thyolo focus, although the number of persons blind from onchocerciasis is probably less than 300.",
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AU - Burnham, Gilbert M

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AB - Skin snips from 23 373 persons living in the Thyolo (formerly Cholp) highlands focus of southern Malawi showed infection with Onchocerca volvulus to be unevenly distributed within the highland area. In the centre of the focus most adults were infected, though intensity of infection was light, not exceeding a geometric mean of 8 microfilariae per mg of skin. It was estimated that 327 000 persons live in areas where prevalence of infection exceeds 10% and, of these, 94 500 persons over the age of one year are infected with O. volvulus. There is a significant relationship between infection with O. volvulus and bilateral blindness in the Thyolo focus, although the number of persons blind from onchocerciasis is probably less than 300.

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