On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

Rakesh K. Saunthwal; Monika Patel; Rakesh K. Tiwari; Keykavous Parang; Akhilesh K. Verma

doi:10.1039/c4gc02154a

On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

Rakesh K. Saunthwal, Monika Patel, Rakesh K. Tiwari, Keykavous Parang, Akhilesh K. Verma

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

A green and catalyst-free atom-ecomonic straightforward tandem approach for the synthesis of highly functionalized tetrahydroquinazolines by the reaction of 2-aminophenylacrylates with isothiocyanates using water as an environmentally friendly solvent via amidation and concomitant chemoselective Michael-addition is described. This journal is

Original language	English (US)
Pages (from-to)	1434-1441
Number of pages	8
Journal	Green Chemistry
Volume	17
Issue number	3
DOIs	https://doi.org/10.1039/c4gc02154a
State	Published - Mar 1 2015
Externally published	Yes

ASJC Scopus subject areas

Environmental Chemistry
Pollution

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10.1039/c4gc02154a

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On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

Abstract

ASJC Scopus subject areas

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