On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

Rakesh K. Saunthwal, Monika Patel, Rakesh K. Tiwari, Keykavous Parang, Akhilesh K. Verma

Research output: Contribution to journalArticle

Abstract

A green and catalyst-free atom-ecomonic straightforward tandem approach for the synthesis of highly functionalized tetrahydroquinazolines by the reaction of 2-aminophenylacrylates with isothiocyanates using water as an environmentally friendly solvent via amidation and concomitant chemoselective Michael-addition is described. This journal is

Original languageEnglish (US)
Pages (from-to)1434-1441
Number of pages8
JournalGreen Chemistry
Volume17
Issue number3
DOIs
StatePublished - Mar 1 2015
Externally publishedYes

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Isothiocyanates
catalyst
Atoms
Catalysts
Water
water

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution

Cite this

On water : Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate. / Saunthwal, Rakesh K.; Patel, Monika; Tiwari, Rakesh K.; Parang, Keykavous; Verma, Akhilesh K.

In: Green Chemistry, Vol. 17, No. 3, 01.03.2015, p. 1434-1441.

Research output: Contribution to journalArticle

Saunthwal, Rakesh K. ; Patel, Monika ; Tiwari, Rakesh K. ; Parang, Keykavous ; Verma, Akhilesh K. / On water : Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate. In: Green Chemistry. 2015 ; Vol. 17, No. 3. pp. 1434-1441.
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