On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

Rakesh K. Saunthwal; Monika Patel; Rakesh K. Tiwari; Keykavous Parang; Akhilesh K. Verma

doi:10.1039/c4gc02154a

On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

Rakesh K. Saunthwal, Monika Patel, Rakesh K. Tiwari, Keykavous Parang, Akhilesh K. Verma

Research output: Contribution to journal › Article

Abstract

A green and catalyst-free atom-ecomonic straightforward tandem approach for the synthesis of highly functionalized tetrahydroquinazolines by the reaction of 2-aminophenylacrylates with isothiocyanates using water as an environmentally friendly solvent via amidation and concomitant chemoselective Michael-addition is described. This journal is

Original language	English (US)
Pages (from-to)	1434-1441
Number of pages	8
Journal	Green Chemistry
Volume	17
Issue number	3
DOIs	https://doi.org/10.1039/c4gc02154a
State	Published - Mar 1 2015
Externally published	Yes

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Isothiocyanates

catalyst

Atoms

Catalysts

Water

water

ASJC Scopus subject areas

Environmental Chemistry
Pollution

Cite this

Saunthwal, R. K., Patel, M., Tiwari, R. K., Parang, K., & Verma, A. K. (2015). On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate. Green Chemistry, 17(3), 1434-1441. https://doi.org/10.1039/c4gc02154a

On water : Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate. / Saunthwal, Rakesh K.; Patel, Monika; Tiwari, Rakesh K.; Parang, Keykavous; Verma, Akhilesh K.

In: Green Chemistry, Vol. 17, No. 3, 01.03.2015, p. 1434-1441.

Research output: Contribution to journal › Article

Saunthwal, RK, Patel, M, Tiwari, RK, Parang, K & Verma, AK 2015, 'On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate', Green Chemistry, vol. 17, no. 3, pp. 1434-1441. https://doi.org/10.1039/c4gc02154a

Saunthwal RK, Patel M, Tiwari RK, Parang K, Verma AK. On water: Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate. Green Chemistry. 2015 Mar 1;17(3):1434-1441. https://doi.org/10.1039/c4gc02154a

Saunthwal, Rakesh K. ; Patel, Monika ; Tiwari, Rakesh K. ; Parang, Keykavous ; Verma, Akhilesh K. / On water : Catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate. In: Green Chemistry. 2015 ; Vol. 17, No. 3. pp. 1434-1441.

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Access to Document

10.1039/c4gc02154a