On the road to repair: PCNA encounters SUMO and ubiquitin modifications

Michael J. Matunis

doi:10.1016/S1097-2765(02)00653-6

On the road to repair: PCNA encounters SUMO and ubiquitin modifications

Michael J. Matunis

Bloomberg School of Public Health

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

The molecular events and targets regulated by the RAD6 pathway, which mediates postreplication DNA repair, have remained elusive. Now, ubiquitin and SUMO modification of proliferating cell nuclear antigen (PCNA) is shown to be induced by DNA damage and linked to components of the RAD6 pathway.

Original language	English (US)
Pages (from-to)	441-442
Number of pages	2
Journal	Molecular cell
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/S1097-2765(02)00653-6
State	Published - Sep 1 2002

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/S1097-2765(02)00653-6

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title = "On the road to repair: PCNA encounters SUMO and ubiquitin modifications",

abstract = "The molecular events and targets regulated by the RAD6 pathway, which mediates postreplication DNA repair, have remained elusive. Now, ubiquitin and SUMO modification of proliferating cell nuclear antigen (PCNA) is shown to be induced by DNA damage and linked to components of the RAD6 pathway.",

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AB - The molecular events and targets regulated by the RAD6 pathway, which mediates postreplication DNA repair, have remained elusive. Now, ubiquitin and SUMO modification of proliferating cell nuclear antigen (PCNA) is shown to be induced by DNA damage and linked to components of the RAD6 pathway.

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On the road to repair: PCNA encounters SUMO and ubiquitin modifications

Abstract

ASJC Scopus subject areas

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