On the emergence of Candida auris: Climate change, azoles, swamps and birds

Arturo Casadevall; Dimitrios P. Kontoyiannis; Vincent Robert

doi:10.1101/657635

On the emergence of Candida auris: Climate change, azoles, swamps and birds

Arturo Casadevall, Dimitrios P. Kontoyiannis, Vincent Robert

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

The most enigmatic aspect of the rise of Candida auris as a human pathogen is that it emerged simultaneously in three continents with each clade being genetically distinct. Although new pathogenic fungal species are described regularly, these are mostly species associated with single cases in individuals who are immunosuppressed. In this study, we used phylogenetic analysis to compare C. auris with temperature susceptibility of close relatives and use these results to argue that it may be the first example of a new fungal disease emerging from climate change with the caveat that many other factors could have contributed.

Original language	English (US)
Journal	Unknown Journal
DOIs	https://doi.org/10.1101/657635
State	Published - Jun 3 2019

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)
Immunology and Microbiology(all)
Neuroscience(all)
Pharmacology, Toxicology and Pharmaceutics(all)

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10.1101/657635

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abstract = "The most enigmatic aspect of the rise of Candida auris as a human pathogen is that it emerged simultaneously in three continents with each clade being genetically distinct. Although new pathogenic fungal species are described regularly, these are mostly species associated with single cases in individuals who are immunosuppressed. In this study, we used phylogenetic analysis to compare C. auris with temperature susceptibility of close relatives and use these results to argue that it may be the first example of a new fungal disease emerging from climate change with the caveat that many other factors could have contributed.",

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