On estimating the directionality distribution in pedicle trabecular bone from micro-CT images

Catherine M. Gdyczynski, Amir Manbachi, Sayed Masoud Hashemi, Bahman Lashkari, Richard S C Cobbold

Research output: Contribution to journalArticle

Abstract

Our interest in the trabecular alignment within bone stems from the need to better understand the manner in which it can affect ultrasound propagation, particularly in pedicles. Within long bones it is well established that trabecular structures are aligned in an organized manner associated with the direction of load distribution; however, for smaller bones there are limited alignment studies. To investigate the directionality distribution in a quantitative manner we used a micro-CT to obtain three-dimensional (3D) structural data and developed analytical methods based on the special properties of Gabor filters. Implementation of these techniques has been developed and tested on a variety of simulated images as well as on 3D structures whose geometry is well-defined. To test the use of this technique we compared the results obtained on vertebral body trabecular bone with visual directionality and previous measurements by others. The method has been applied to six human pedicle samples in two orthogonal planes with results that provide reasonable proof-of-principle evidence that the method is well suited for estimating the directionality distribution within pedicle bones.

Original languageEnglish (US)
Pages (from-to)2415-2428
Number of pages14
JournalPhysiological Measurement
Volume35
Issue number12
DOIs
StatePublished - Dec 1 2014
Externally publishedYes

Fingerprint

Bone
Bone and Bones
Gabor filters
Ultrasonics
Cancellous Bone
Geometry

Keywords

  • Bone directionality
  • Gabor filter
  • micro-CT
  • pedicle bone
  • trabecular bone

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Physiology (medical)
  • Medicine(all)

Cite this

On estimating the directionality distribution in pedicle trabecular bone from micro-CT images. / Gdyczynski, Catherine M.; Manbachi, Amir; Hashemi, Sayed Masoud; Lashkari, Bahman; Cobbold, Richard S C.

In: Physiological Measurement, Vol. 35, No. 12, 01.12.2014, p. 2415-2428.

Research output: Contribution to journalArticle

Gdyczynski, Catherine M. ; Manbachi, Amir ; Hashemi, Sayed Masoud ; Lashkari, Bahman ; Cobbold, Richard S C. / On estimating the directionality distribution in pedicle trabecular bone from micro-CT images. In: Physiological Measurement. 2014 ; Vol. 35, No. 12. pp. 2415-2428.
@article{58d872124ce44c458996984ba63da133,
title = "On estimating the directionality distribution in pedicle trabecular bone from micro-CT images",
abstract = "Our interest in the trabecular alignment within bone stems from the need to better understand the manner in which it can affect ultrasound propagation, particularly in pedicles. Within long bones it is well established that trabecular structures are aligned in an organized manner associated with the direction of load distribution; however, for smaller bones there are limited alignment studies. To investigate the directionality distribution in a quantitative manner we used a micro-CT to obtain three-dimensional (3D) structural data and developed analytical methods based on the special properties of Gabor filters. Implementation of these techniques has been developed and tested on a variety of simulated images as well as on 3D structures whose geometry is well-defined. To test the use of this technique we compared the results obtained on vertebral body trabecular bone with visual directionality and previous measurements by others. The method has been applied to six human pedicle samples in two orthogonal planes with results that provide reasonable proof-of-principle evidence that the method is well suited for estimating the directionality distribution within pedicle bones.",
keywords = "Bone directionality, Gabor filter, micro-CT, pedicle bone, trabecular bone",
author = "Gdyczynski, {Catherine M.} and Amir Manbachi and Hashemi, {Sayed Masoud} and Bahman Lashkari and Cobbold, {Richard S C}",
year = "2014",
month = "12",
day = "1",
doi = "10.1088/0967-3334/35/12/2415",
language = "English (US)",
volume = "35",
pages = "2415--2428",
journal = "Physiological Measurement",
issn = "0967-3334",
publisher = "IOP Publishing Ltd.",
number = "12",

}

TY - JOUR

T1 - On estimating the directionality distribution in pedicle trabecular bone from micro-CT images

AU - Gdyczynski, Catherine M.

AU - Manbachi, Amir

AU - Hashemi, Sayed Masoud

AU - Lashkari, Bahman

AU - Cobbold, Richard S C

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Our interest in the trabecular alignment within bone stems from the need to better understand the manner in which it can affect ultrasound propagation, particularly in pedicles. Within long bones it is well established that trabecular structures are aligned in an organized manner associated with the direction of load distribution; however, for smaller bones there are limited alignment studies. To investigate the directionality distribution in a quantitative manner we used a micro-CT to obtain three-dimensional (3D) structural data and developed analytical methods based on the special properties of Gabor filters. Implementation of these techniques has been developed and tested on a variety of simulated images as well as on 3D structures whose geometry is well-defined. To test the use of this technique we compared the results obtained on vertebral body trabecular bone with visual directionality and previous measurements by others. The method has been applied to six human pedicle samples in two orthogonal planes with results that provide reasonable proof-of-principle evidence that the method is well suited for estimating the directionality distribution within pedicle bones.

AB - Our interest in the trabecular alignment within bone stems from the need to better understand the manner in which it can affect ultrasound propagation, particularly in pedicles. Within long bones it is well established that trabecular structures are aligned in an organized manner associated with the direction of load distribution; however, for smaller bones there are limited alignment studies. To investigate the directionality distribution in a quantitative manner we used a micro-CT to obtain three-dimensional (3D) structural data and developed analytical methods based on the special properties of Gabor filters. Implementation of these techniques has been developed and tested on a variety of simulated images as well as on 3D structures whose geometry is well-defined. To test the use of this technique we compared the results obtained on vertebral body trabecular bone with visual directionality and previous measurements by others. The method has been applied to six human pedicle samples in two orthogonal planes with results that provide reasonable proof-of-principle evidence that the method is well suited for estimating the directionality distribution within pedicle bones.

KW - Bone directionality

KW - Gabor filter

KW - micro-CT

KW - pedicle bone

KW - trabecular bone

UR - http://www.scopus.com/inward/record.url?scp=84915826289&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84915826289&partnerID=8YFLogxK

U2 - 10.1088/0967-3334/35/12/2415

DO - 10.1088/0967-3334/35/12/2415

M3 - Article

C2 - 25391037

AN - SCOPUS:84915826289

VL - 35

SP - 2415

EP - 2428

JO - Physiological Measurement

JF - Physiological Measurement

SN - 0967-3334

IS - 12

ER -