On corneal transparency and its loss with swelling.

R. A. Farrell, R. L. McCally

Research output: Contribution to journalArticle

Abstract

The cornea is the clear front covering of the eye through which we see and is composed of collagen fibrils embedded in an optically homogeneous ground substance. It has long been recognized that these fibrils scatter light and that transparency results from interference effects due to an ordering in the spatial arrangement of the fibrils about one another. The nature of this ordering and of its disruption in abnormal corneas is of great current interest. The present study reviews experimental light scattering and electron microscopic evidence relevant to this problem. This evidence suggests that theoretical attempts to model and understand corneal transparency and its loss during swelling, in terms of ultrastructure, must account for a short-ranged ordering of fibrils in normal healthy corneas and for the formation of regions void of fibrils in swollen corneas.

Original languageEnglish (US)
Pages (from-to)342
Number of pages1
JournalJournal of the Optical Society of America
Volume66
Issue number4
StatePublished - Apr 1976
Externally publishedYes

Fingerprint

Cornea
Transparency
Swelling
Collagen
Light scattering
Light
Electrons

ASJC Scopus subject areas

  • Medicine(all)

Cite this

On corneal transparency and its loss with swelling. / Farrell, R. A.; McCally, R. L.

In: Journal of the Optical Society of America, Vol. 66, No. 4, 04.1976, p. 342.

Research output: Contribution to journalArticle

Farrell, RA & McCally, RL 1976, 'On corneal transparency and its loss with swelling.', Journal of the Optical Society of America, vol. 66, no. 4, pp. 342.
Farrell, R. A. ; McCally, R. L. / On corneal transparency and its loss with swelling. In: Journal of the Optical Society of America. 1976 ; Vol. 66, No. 4. pp. 342.
@article{99e75c9cf4bf4c528d3d0c9296c8719f,
title = "On corneal transparency and its loss with swelling.",
abstract = "The cornea is the clear front covering of the eye through which we see and is composed of collagen fibrils embedded in an optically homogeneous ground substance. It has long been recognized that these fibrils scatter light and that transparency results from interference effects due to an ordering in the spatial arrangement of the fibrils about one another. The nature of this ordering and of its disruption in abnormal corneas is of great current interest. The present study reviews experimental light scattering and electron microscopic evidence relevant to this problem. This evidence suggests that theoretical attempts to model and understand corneal transparency and its loss during swelling, in terms of ultrastructure, must account for a short-ranged ordering of fibrils in normal healthy corneas and for the formation of regions void of fibrils in swollen corneas.",
author = "Farrell, {R. A.} and McCally, {R. L.}",
year = "1976",
month = "4",
language = "English (US)",
volume = "66",
pages = "342",
journal = "Journal of the Optical Society of America",
issn = "0030-3941",
publisher = "The Optical Society",
number = "4",

}

TY - JOUR

T1 - On corneal transparency and its loss with swelling.

AU - Farrell, R. A.

AU - McCally, R. L.

PY - 1976/4

Y1 - 1976/4

N2 - The cornea is the clear front covering of the eye through which we see and is composed of collagen fibrils embedded in an optically homogeneous ground substance. It has long been recognized that these fibrils scatter light and that transparency results from interference effects due to an ordering in the spatial arrangement of the fibrils about one another. The nature of this ordering and of its disruption in abnormal corneas is of great current interest. The present study reviews experimental light scattering and electron microscopic evidence relevant to this problem. This evidence suggests that theoretical attempts to model and understand corneal transparency and its loss during swelling, in terms of ultrastructure, must account for a short-ranged ordering of fibrils in normal healthy corneas and for the formation of regions void of fibrils in swollen corneas.

AB - The cornea is the clear front covering of the eye through which we see and is composed of collagen fibrils embedded in an optically homogeneous ground substance. It has long been recognized that these fibrils scatter light and that transparency results from interference effects due to an ordering in the spatial arrangement of the fibrils about one another. The nature of this ordering and of its disruption in abnormal corneas is of great current interest. The present study reviews experimental light scattering and electron microscopic evidence relevant to this problem. This evidence suggests that theoretical attempts to model and understand corneal transparency and its loss during swelling, in terms of ultrastructure, must account for a short-ranged ordering of fibrils in normal healthy corneas and for the formation of regions void of fibrils in swollen corneas.

UR - http://www.scopus.com/inward/record.url?scp=0016945249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016945249&partnerID=8YFLogxK

M3 - Article

C2 - 1262983

VL - 66

SP - 342

JO - Journal of the Optical Society of America

JF - Journal of the Optical Society of America

SN - 0030-3941

IS - 4

ER -