Abstract
Introduction: The utility of the greater omentum has not been assessed in transluminal access closure after natural orifice transluminal endoscopic surgery (NOTES) procedures. Objective: Our purpose was to evaluate the feasibility, efficacy, and safety of omentoplasty for gastrotomy closure. Methods and Procedures: Survival experiments in 9 female 40-kg pigs were randomly assigned to 3 groups: group A, endoscopic full-thickness resection (EFTR) for transgastric access and peritoneoscopy without closure; group B, ETFR and peritoneoscopy with omentoplasty (flap of omentum is pulled into the stomach and attached to the gastric mucosa with clips but no clips are used for gastrotomy closure itself); group C, balloon dilation for opening and peritoneoscopy followed by omentoplasty for closure. The animals were observed for 2 weeks and then underwent endoscopy and necropsy with histologic evaluation. Results: Transgastric opening and peritoneoscopy were achieved in all pigs. In groups B and C, a flap of omentum was easily placed to seal the gastrotomy and then attached to the gastric mucosa with 2 to 5 clips (median 4) in 7 to 20 minutes (median 15 minutes). In group A, peritonitis developed in all animals. In both groups B and C, all animals survived 15 days with no peritonitis and minimal adhesions outside the gastrotomy site. In addition, all achieved complete healing (transmural, n = 4; mucosal ulceration, n = 2) of the gastrotomy site. One animal in group B had an 18-mm abscess in the omental flap. Limitations: Animal model, small sample size, lack of appropriate controls for group C. Conclusions: Omentoplasty of the gastrotomy site is a technically feasible method to seal balloon-created transgastric access to the peritoneal cavity after NOTES procedures.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 131-140 |
| Number of pages | 10 |
| Journal | Gastrointestinal Endoscopy |
| Volume | 70 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 2009 |
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ASJC Scopus subject areas
- Gastroenterology
- Radiology Nuclear Medicine and imaging
Cite this
Omentoplasty for gastrotomy closure after natural orifice transluminal endoscopic surgery procedures (with video). / Dray, Xavier; Giday, Samuel A.; Buscaglia, Jonathan M.; Gabrielson, Kathleen L; Kantsevoy, Sergey V.; Magno, Priscilla; Assumpcao, Lia; Shin, Eun; Reddings, Susan K.; Woods, Kevin E.; Marohn, Michael; Kalloo, Anthony N.
In: Gastrointestinal Endoscopy, Vol. 70, No. 1, 07.2009, p. 131-140.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Omentoplasty for gastrotomy closure after natural orifice transluminal endoscopic surgery procedures (with video)
AU - Dray, Xavier
AU - Giday, Samuel A.
AU - Buscaglia, Jonathan M.
AU - Gabrielson, Kathleen L
AU - Kantsevoy, Sergey V.
AU - Magno, Priscilla
AU - Assumpcao, Lia
AU - Shin, Eun
AU - Reddings, Susan K.
AU - Woods, Kevin E.
AU - Marohn, Michael
AU - Kalloo, Anthony N
PY - 2009/7
Y1 - 2009/7
N2 - Introduction: The utility of the greater omentum has not been assessed in transluminal access closure after natural orifice transluminal endoscopic surgery (NOTES) procedures. Objective: Our purpose was to evaluate the feasibility, efficacy, and safety of omentoplasty for gastrotomy closure. Methods and Procedures: Survival experiments in 9 female 40-kg pigs were randomly assigned to 3 groups: group A, endoscopic full-thickness resection (EFTR) for transgastric access and peritoneoscopy without closure; group B, ETFR and peritoneoscopy with omentoplasty (flap of omentum is pulled into the stomach and attached to the gastric mucosa with clips but no clips are used for gastrotomy closure itself); group C, balloon dilation for opening and peritoneoscopy followed by omentoplasty for closure. The animals were observed for 2 weeks and then underwent endoscopy and necropsy with histologic evaluation. Results: Transgastric opening and peritoneoscopy were achieved in all pigs. In groups B and C, a flap of omentum was easily placed to seal the gastrotomy and then attached to the gastric mucosa with 2 to 5 clips (median 4) in 7 to 20 minutes (median 15 minutes). In group A, peritonitis developed in all animals. In both groups B and C, all animals survived 15 days with no peritonitis and minimal adhesions outside the gastrotomy site. In addition, all achieved complete healing (transmural, n = 4; mucosal ulceration, n = 2) of the gastrotomy site. One animal in group B had an 18-mm abscess in the omental flap. Limitations: Animal model, small sample size, lack of appropriate controls for group C. Conclusions: Omentoplasty of the gastrotomy site is a technically feasible method to seal balloon-created transgastric access to the peritoneal cavity after NOTES procedures.
AB - Introduction: The utility of the greater omentum has not been assessed in transluminal access closure after natural orifice transluminal endoscopic surgery (NOTES) procedures. Objective: Our purpose was to evaluate the feasibility, efficacy, and safety of omentoplasty for gastrotomy closure. Methods and Procedures: Survival experiments in 9 female 40-kg pigs were randomly assigned to 3 groups: group A, endoscopic full-thickness resection (EFTR) for transgastric access and peritoneoscopy without closure; group B, ETFR and peritoneoscopy with omentoplasty (flap of omentum is pulled into the stomach and attached to the gastric mucosa with clips but no clips are used for gastrotomy closure itself); group C, balloon dilation for opening and peritoneoscopy followed by omentoplasty for closure. The animals were observed for 2 weeks and then underwent endoscopy and necropsy with histologic evaluation. Results: Transgastric opening and peritoneoscopy were achieved in all pigs. In groups B and C, a flap of omentum was easily placed to seal the gastrotomy and then attached to the gastric mucosa with 2 to 5 clips (median 4) in 7 to 20 minutes (median 15 minutes). In group A, peritonitis developed in all animals. In both groups B and C, all animals survived 15 days with no peritonitis and minimal adhesions outside the gastrotomy site. In addition, all achieved complete healing (transmural, n = 4; mucosal ulceration, n = 2) of the gastrotomy site. One animal in group B had an 18-mm abscess in the omental flap. Limitations: Animal model, small sample size, lack of appropriate controls for group C. Conclusions: Omentoplasty of the gastrotomy site is a technically feasible method to seal balloon-created transgastric access to the peritoneal cavity after NOTES procedures.
UR - http://www.scopus.com/inward/record.url?scp=67649259227&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67649259227&partnerID=8YFLogxK
U2 - 10.1016/j.gie.2008.10.035
DO - 10.1016/j.gie.2008.10.035
M3 - Article
C2 - 19394007
AN - SCOPUS:67649259227
VL - 70
SP - 131
EP - 140
JO - Gastrointestinal Endoscopy
JF - Gastrointestinal Endoscopy
SN - 0016-5107
IS - 1
ER -