Office-based Management of Recurrent Respiratory Papilloma

Research output: Contribution to journalReview articlepeer-review

Abstract

This review will highlight the indications and benefits of office-based therapy for recurrent respiratory papillomatosis (RRP) and discuss the utilization of photodynamic lasers and adjuvant medical therapy in office-based settings. Office-based management of RRP allows for more timely interventions, is preferred by the majority of patients, and negates the risk of general anesthesia. Current literature argues for the utilization of KTP laser over CO2 laser for office-based treatment of RRP. Medical therapies for RRP are limited, but agents such as bevacizumab are promising and have been shown to reduce disease burden. Medical therapies that can induce disease remission are still needed. Office-based procedures save time and healthcare expenses compared to like procedures in the operating room. However, the increased frequency for office-based procedures predicts similar overall healthcare costs for office-based and OR laser excision of RRP. Office-based management of RRP is a feasible and well-tolerated strategy in appropriately selected patients with adequate local anesthesia.

Original languageEnglish (US)
Pages (from-to)90-98
Number of pages9
JournalCurrent Otorhinolaryngology Reports
Volume4
Issue number2
DOIs
StatePublished - Jun 2016

Keywords

  • Bevacizumab
  • HPV
  • Human papillomavirus
  • KTP laser
  • Office-based laryngology procedures
  • Potassium titanyl phosphate laser
  • RRP
  • Recurrent respiratory papillomatosis

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery
  • Immunology and Allergy
  • Clinical Neurology

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