Of postulates and peccadilloes: Robert Koch and vaccine (tuberculin) therapy for tuberculosis

Donald S. Burke

Research output: Contribution to journalArticle

Abstract

In August 1890, Robert Koch dramatically announced that he had discovered a cure for tuberculosis, and the world rejoiced. The miracle substance was subsequently revealed to be tuberculin, inoculated as a 'vaccine therapy'. However, within a matter of months his claims were disputed and debunked, and his reputation was grievously damaged. The nationalistic pressures, professional jealousies and pecuniary interests that drove Koch's premature announcement are reviewed here and discussed in a context relevant to the development of therapeutic vaccines for human immunodeficiency virus infections.

Original languageEnglish (US)
Pages (from-to)795-804
Number of pages10
JournalVaccine
Volume11
Issue number8
DOIs
StatePublished - 1993
Externally publishedYes

Fingerprint

Active Immunotherapy
tuberculin
Tuberculin
Virus Diseases
tuberculosis
Tuberculosis
Vaccines
HIV
vaccines
Pressure
therapeutics
HIV infections
Therapeutics

Keywords

  • HIV
  • Koch
  • tuberculosis
  • vaccine therapy

ASJC Scopus subject areas

  • Immunology
  • Microbiology
  • Virology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)

Cite this

Of postulates and peccadilloes : Robert Koch and vaccine (tuberculin) therapy for tuberculosis. / Burke, Donald S.

In: Vaccine, Vol. 11, No. 8, 1993, p. 795-804.

Research output: Contribution to journalArticle

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