Of mice and men, periodic limb movements and iron: How the human genome informs the mouse genome

L. C. Jones, C. J. Earley, R. P. Allen, B. C. Jones

Research output: Contribution to journalComment/debate

Abstract

The gene, BTBD9, was recently linked to restless legs syndrome, periodic limb movements and iron status in humans. In a homologous region in mouse, an area containing btbd9 was also identified as being related to iron homeostasis. This finding is important as iron status in brain has been implicated in restless legs syndrome.

Original languageEnglish (US)
Pages (from-to)513-514
Number of pages2
JournalGenes, Brain and Behavior
Volume7
Issue number5
DOIs
StatePublished - Jul 1 2008

Keywords

  • Btbd9
  • Bxd
  • Glo1
  • Iron
  • Qtl

ASJC Scopus subject areas

  • Genetics
  • Neurology
  • Behavioral Neuroscience

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