Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function

J. Pevsner; P. M. Hwang; P. B. Sklar; J. C. Venable; S. H. Snyder

doi:10.1073/pnas.85.7.2383

Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function

J. Pevsner, P. M. Hwang, P. B. Sklar, J. C. Venable, S. H. Snyder

School of Medicine

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Odorant-binding protein selectively binds various odorants and is discretely concentrated in nasal mucosa and secretions. We have localized rat odorant-binding protein mRNA to the lateral nasal gland by in situ hybridization histochemistry and have also localized the protein to this gland by immunohistochemistry and by tritiated-odorant autoradiography. The lateral nasal gland extends a long duct toward the external nares. Odorant-binding protein, released from this duct, may transport odorants to olfactory receptor neurons.

Original language	English (US)
Pages (from-to)	2383-2387
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	85
Issue number	7
DOIs	https://doi.org/10.1073/pnas.85.7.2383
State	Published - 1988

Keywords

immunohistochemistry
in situ hybridization
odorant autoradiogaphy
olfaction

ASJC Scopus subject areas

General

Access to Document

10.1073/pnas.85.7.2383

Cite this

@article{0932b8cc6e12459b8289200101330b8a,

title = "Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function",

abstract = "Odorant-binding protein selectively binds various odorants and is discretely concentrated in nasal mucosa and secretions. We have localized rat odorant-binding protein mRNA to the lateral nasal gland by in situ hybridization histochemistry and have also localized the protein to this gland by immunohistochemistry and by tritiated-odorant autoradiography. The lateral nasal gland extends a long duct toward the external nares. Odorant-binding protein, released from this duct, may transport odorants to olfactory receptor neurons.",

keywords = "immunohistochemistry, in situ hybridization, odorant autoradiogaphy, olfaction",

author = "J. Pevsner and Hwang, {P. M.} and Sklar, {P. B.} and Venable, {J. C.} and Snyder, {S. H.}",

year = "1988",

doi = "10.1073/pnas.85.7.2383",

language = "English (US)",

volume = "85",

pages = "2383--2387",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

number = "7",

}

TY - JOUR

T1 - Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function

AU - Pevsner, J.

AU - Hwang, P. M.

AU - Sklar, P. B.

AU - Venable, J. C.

AU - Snyder, S. H.

PY - 1988

Y1 - 1988

N2 - Odorant-binding protein selectively binds various odorants and is discretely concentrated in nasal mucosa and secretions. We have localized rat odorant-binding protein mRNA to the lateral nasal gland by in situ hybridization histochemistry and have also localized the protein to this gland by immunohistochemistry and by tritiated-odorant autoradiography. The lateral nasal gland extends a long duct toward the external nares. Odorant-binding protein, released from this duct, may transport odorants to olfactory receptor neurons.

AB - Odorant-binding protein selectively binds various odorants and is discretely concentrated in nasal mucosa and secretions. We have localized rat odorant-binding protein mRNA to the lateral nasal gland by in situ hybridization histochemistry and have also localized the protein to this gland by immunohistochemistry and by tritiated-odorant autoradiography. The lateral nasal gland extends a long duct toward the external nares. Odorant-binding protein, released from this duct, may transport odorants to olfactory receptor neurons.

KW - immunohistochemistry

KW - in situ hybridization

KW - odorant autoradiogaphy

KW - olfaction

UR - http://www.scopus.com/inward/record.url?scp=0024121478&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024121478&partnerID=8YFLogxK

U2 - 10.1073/pnas.85.7.2383

DO - 10.1073/pnas.85.7.2383

M3 - Article

C2 - 3353387

AN - SCOPUS:0024121478

SN - 0027-8424

VL - 85

SP - 2383

EP - 2387

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 7

ER -

Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this