Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function

J. Pevsner, P. M. Hwang, P. B. Sklar, J. C. Venable, S. H. Snyder

Research output: Contribution to journalArticlepeer-review

Abstract

Odorant-binding protein selectively binds various odorants and is discretely concentrated in nasal mucosa and secretions. We have localized rat odorant-binding protein mRNA to the lateral nasal gland by in situ hybridization histochemistry and have also localized the protein to this gland by immunohistochemistry and by tritiated-odorant autoradiography. The lateral nasal gland extends a long duct toward the external nares. Odorant-binding protein, released from this duct, may transport odorants to olfactory receptor neurons.

Original languageEnglish (US)
Pages (from-to)2383-2387
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume85
Issue number7
DOIs
StatePublished - 1988

Keywords

  • immunohistochemistry
  • in situ hybridization
  • odorant autoradiogaphy
  • olfaction

ASJC Scopus subject areas

  • General

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