Ocular manifestations of sickle hemoglobinopathies

Krishan C. Nagpal, Morton F. Goldberg, Maurice F. Rabb

Research output: Contribution to journalReview articlepeer-review

67 Scopus citations


The ocular manifestations of sickle cell hemoglobinopathies, while often not severe enough to affect vision, may develop in proliferative stages, resulting in arteriolar-venular anastomoses, neovascular proliferations, vitreous hemorrhage and retinal detachment. The authors review the historical, biochemical, and geographic aspects of the disease, and provide detailed descriptions of findings in the conjunctiva, uvea and fundus, with particular emphasis on the retina. Pathogenesis, histopathologic and clinical appearance, and modes of treatment are discussed.

Original languageEnglish (US)
Pages (from-to)391-411
Number of pages21
JournalSurvey of ophthalmology
Issue number5
StatePublished - Jan 1 1977
Externally publishedYes


  • argon laser
  • black sunburst
  • cryopexy
  • hemoglobinopathy
  • photocoagulation
  • retinopathy
  • salmon patch
  • sea fan
  • sickle cell disease
  • xenon arc

ASJC Scopus subject areas

  • Ophthalmology


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