Octreotide in children with hypoglycaemia due to sulfonylurea ingestion

Shoshana Rath, Naor Bar-Zeev, Kym Anderson, Rosemary Fahy, Rob Roseby

Research output: Contribution to journalArticle

Abstract

Sulfonylureas are commonly prescribed for type 2 diabetes mellitus; however, overdose or accidental ingestion may result in profound and prolonged hypoglycaemia with permanent neurological sequelae and death. We describe two cases of children with hypoglycaemia due to presumed accidental ingestion of sulfonylureas, where traditional methods of raising blood sugar levels were unsatisfactory. Two studies describe Octreotide for adults with hypoglycaemia, but there are no studies examining the use of Octreotide in children for this indication. Given that Octreotide has been shown to be safe in children when used for other indications, we used Octreotide to safely restore euglycaemia.

Original languageEnglish (US)
Pages (from-to)383-384
Number of pages2
JournalJournal of Paediatrics and Child Health
Volume44
Issue number6
DOIs
StatePublished - Jun 1 2008
Externally publishedYes

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Keywords

  • Children
  • Hypoglycaemia
  • Octreotide
  • Overdose
  • Sulfonylurea compounds

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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