OCT imaging of osteoarthritic cartilage: Structure, polarization sensitivity, and clinical feasibility

Xingde Li; Jurgen Herrmann; Ravi Ghanta; Costas Pitris; Wolfgang Drexler; Christine Jesser; Debra Stamper; David Golden; Scott Martin; James G. Fujimoto; Mark Brezinski

OCT imaging of osteoarthritic cartilage: Structure, polarization sensitivity, and clinical feasibility

Xingde Li, Jurgen Herrmann, Ravi Ghanta, Costas Pitris, Wolfgang Drexler, Christine Jesser, Debra Stamper, David Golden, Scott Martin, James G. Fujimoto, Mark Brezinski

Research output: Contribution to journal › Conference article › peer-review

6 Scopus citations

Abstract

This work demonstrates the feasibility of Optical Coherence Tomography (OCT) for identifying early osteoarthritic pathology. In addition to structural abnormalities, changes in collagen fiber organization, an indicator of very early osteoarthritis, were assessed with a polarization sensitive OCT system. A portable, real time, modular OCT system, suitable for both laboratory and clinical settings, has been developed. Preliminary in vivo imaging results obtained during partial knee replacement surgery are discussed.

Original language	English (US)
Pages (from-to)	152-157
Number of pages	6
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3598
State	Published - Jan 1 1999
Externally published	Yes
Event	Proceedings of the 1999 Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III - San Jose, CA, USA Duration: Jan 27 1999 → Jan 29 1999

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Cite this

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title = "OCT imaging of osteoarthritic cartilage: Structure, polarization sensitivity, and clinical feasibility",

abstract = "This work demonstrates the feasibility of Optical Coherence Tomography (OCT) for identifying early osteoarthritic pathology. In addition to structural abnormalities, changes in collagen fiber organization, an indicator of very early osteoarthritis, were assessed with a polarization sensitive OCT system. A portable, real time, modular OCT system, suitable for both laboratory and clinical settings, has been developed. Preliminary in vivo imaging results obtained during partial knee replacement surgery are discussed.",

author = "Xingde Li and Jurgen Herrmann and Ravi Ghanta and Costas Pitris and Wolfgang Drexler and Christine Jesser and Debra Stamper and David Golden and Scott Martin and Fujimoto, {James G.} and Mark Brezinski",

year = "1999",

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pages = "152--157",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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note = "Proceedings of the 1999 Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III ; Conference date: 27-01-1999 Through 29-01-1999",

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T1 - OCT imaging of osteoarthritic cartilage

T2 - Proceedings of the 1999 Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III

AU - Li, Xingde

AU - Herrmann, Jurgen

AU - Ghanta, Ravi

AU - Pitris, Costas

AU - Drexler, Wolfgang

AU - Jesser, Christine

AU - Stamper, Debra

AU - Golden, David

AU - Martin, Scott

AU - Fujimoto, James G.

AU - Brezinski, Mark

PY - 1999/1/1

Y1 - 1999/1/1

N2 - This work demonstrates the feasibility of Optical Coherence Tomography (OCT) for identifying early osteoarthritic pathology. In addition to structural abnormalities, changes in collagen fiber organization, an indicator of very early osteoarthritis, were assessed with a polarization sensitive OCT system. A portable, real time, modular OCT system, suitable for both laboratory and clinical settings, has been developed. Preliminary in vivo imaging results obtained during partial knee replacement surgery are discussed.

AB - This work demonstrates the feasibility of Optical Coherence Tomography (OCT) for identifying early osteoarthritic pathology. In addition to structural abnormalities, changes in collagen fiber organization, an indicator of very early osteoarthritis, were assessed with a polarization sensitive OCT system. A portable, real time, modular OCT system, suitable for both laboratory and clinical settings, has been developed. Preliminary in vivo imaging results obtained during partial knee replacement surgery are discussed.

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UR - http://www.scopus.com/inward/citedby.url?scp=0032687647&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0032687647

SN - 0277-786X

VL - 3598

SP - 152

EP - 157

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

Y2 - 27 January 1999 through 29 January 1999

ER -

OCT imaging of osteoarthritic cartilage: Structure, polarization sensitivity, and clinical feasibility

Abstract

ASJC Scopus subject areas

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