Occurrence of stroke associated with use/abuse of drugs

Michael A. Sloan, Steven J. Kittner, Daniele Rigamonti, Thomas R. Price

Research output: Contribution to journalArticle

Abstract

Ischemic and hemorrhagic stroke frequently occur in temporal association with use or abuse of illicit and over-the-counter (OTC) sympathomimetic drugs. However, little information is available on the proportion of strokes associated with use/abuse of drugs in specific hospital populations. Between September 1, 1988, and August 1, 1989, 167 of 178 stroke patients entered into the Maryland Stroke Data Bank were asked for a history of drug use or abuse. Information was incomplete in 51 of 167 (31%) patients due to neurologic deficit or lack of inquiry. Eleven of the remaining 116 cases (9.5%) were historically associated with drug use. Age range was 25 to 56 years (mean, 41 years). Stroke associated with drug use occurred in four of 62 (6%) cerebral infarcts, two of 28 (7%) intracerebral hemorrhages, and five of 26 (19%) subarachnoid hemorrhages (p = ns). Drugs included cocaine in five (45%), OTC sympathomimetics in three (27%), phencyclidine in two (18%), and heroin in one (9%).

Original languageEnglish (US)
Pages (from-to)1358-1364
Number of pages7
JournalNeurology
Volume41
Issue number9
StatePublished - 1991
Externally publishedYes

Fingerprint

Substance-Related Disorders
Stroke
Sympathomimetics
Pharmaceutical Preparations
Nonprescription Drugs
Phencyclidine
Heroin
Cerebral Hemorrhage
Subarachnoid Hemorrhage
Neurologic Manifestations
Cocaine
Abuse
Drugs
Databases
Population

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Sloan, M. A., Kittner, S. J., Rigamonti, D., & Price, T. R. (1991). Occurrence of stroke associated with use/abuse of drugs. Neurology, 41(9), 1358-1364.

Occurrence of stroke associated with use/abuse of drugs. / Sloan, Michael A.; Kittner, Steven J.; Rigamonti, Daniele; Price, Thomas R.

In: Neurology, Vol. 41, No. 9, 1991, p. 1358-1364.

Research output: Contribution to journalArticle

Sloan, MA, Kittner, SJ, Rigamonti, D & Price, TR 1991, 'Occurrence of stroke associated with use/abuse of drugs', Neurology, vol. 41, no. 9, pp. 1358-1364.
Sloan MA, Kittner SJ, Rigamonti D, Price TR. Occurrence of stroke associated with use/abuse of drugs. Neurology. 1991;41(9):1358-1364.
Sloan, Michael A. ; Kittner, Steven J. ; Rigamonti, Daniele ; Price, Thomas R. / Occurrence of stroke associated with use/abuse of drugs. In: Neurology. 1991 ; Vol. 41, No. 9. pp. 1358-1364.
@article{00c33c8f374142a9a3f88f458236b8fc,
title = "Occurrence of stroke associated with use/abuse of drugs",
abstract = "Ischemic and hemorrhagic stroke frequently occur in temporal association with use or abuse of illicit and over-the-counter (OTC) sympathomimetic drugs. However, little information is available on the proportion of strokes associated with use/abuse of drugs in specific hospital populations. Between September 1, 1988, and August 1, 1989, 167 of 178 stroke patients entered into the Maryland Stroke Data Bank were asked for a history of drug use or abuse. Information was incomplete in 51 of 167 (31{\%}) patients due to neurologic deficit or lack of inquiry. Eleven of the remaining 116 cases (9.5{\%}) were historically associated with drug use. Age range was 25 to 56 years (mean, 41 years). Stroke associated with drug use occurred in four of 62 (6{\%}) cerebral infarcts, two of 28 (7{\%}) intracerebral hemorrhages, and five of 26 (19{\%}) subarachnoid hemorrhages (p = ns). Drugs included cocaine in five (45{\%}), OTC sympathomimetics in three (27{\%}), phencyclidine in two (18{\%}), and heroin in one (9{\%}).",
author = "Sloan, {Michael A.} and Kittner, {Steven J.} and Daniele Rigamonti and Price, {Thomas R.}",
year = "1991",
language = "English (US)",
volume = "41",
pages = "1358--1364",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Occurrence of stroke associated with use/abuse of drugs

AU - Sloan, Michael A.

AU - Kittner, Steven J.

AU - Rigamonti, Daniele

AU - Price, Thomas R.

PY - 1991

Y1 - 1991

N2 - Ischemic and hemorrhagic stroke frequently occur in temporal association with use or abuse of illicit and over-the-counter (OTC) sympathomimetic drugs. However, little information is available on the proportion of strokes associated with use/abuse of drugs in specific hospital populations. Between September 1, 1988, and August 1, 1989, 167 of 178 stroke patients entered into the Maryland Stroke Data Bank were asked for a history of drug use or abuse. Information was incomplete in 51 of 167 (31%) patients due to neurologic deficit or lack of inquiry. Eleven of the remaining 116 cases (9.5%) were historically associated with drug use. Age range was 25 to 56 years (mean, 41 years). Stroke associated with drug use occurred in four of 62 (6%) cerebral infarcts, two of 28 (7%) intracerebral hemorrhages, and five of 26 (19%) subarachnoid hemorrhages (p = ns). Drugs included cocaine in five (45%), OTC sympathomimetics in three (27%), phencyclidine in two (18%), and heroin in one (9%).

AB - Ischemic and hemorrhagic stroke frequently occur in temporal association with use or abuse of illicit and over-the-counter (OTC) sympathomimetic drugs. However, little information is available on the proportion of strokes associated with use/abuse of drugs in specific hospital populations. Between September 1, 1988, and August 1, 1989, 167 of 178 stroke patients entered into the Maryland Stroke Data Bank were asked for a history of drug use or abuse. Information was incomplete in 51 of 167 (31%) patients due to neurologic deficit or lack of inquiry. Eleven of the remaining 116 cases (9.5%) were historically associated with drug use. Age range was 25 to 56 years (mean, 41 years). Stroke associated with drug use occurred in four of 62 (6%) cerebral infarcts, two of 28 (7%) intracerebral hemorrhages, and five of 26 (19%) subarachnoid hemorrhages (p = ns). Drugs included cocaine in five (45%), OTC sympathomimetics in three (27%), phencyclidine in two (18%), and heroin in one (9%).

UR - http://www.scopus.com/inward/record.url?scp=0026069888&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026069888&partnerID=8YFLogxK

M3 - Article

C2 - 1891081

AN - SCOPUS:0026069888

VL - 41

SP - 1358

EP - 1364

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 9

ER -