Occupational and environmental risk factors for chronic rhinosinusitis: A systematic review

Agnes S. Sundaresan, Annemarie G. Hirsch, Margaret Storm, Bruce K. Tan, Thomas L. Kennedy, J. Scott Greene, Robert C. Kern, Brian S Schwartz

Research output: Contribution to journalArticle

Abstract

Background: Chronic rhinosinusitis (CRS) is a prevalent and disabling paranasal sinus disease, with a likely multifactorial etiology potentially including hazardous occupational and environmental exposures. We completed a systematic review of the occupational and environmental literature to evaluate the quality of evidence of the role that hazardous exposures might play in CRS. Methods: We searched PubMed for studies of CRS and following exposure categories: occupation, employment, work, industry, air pollution, agriculture, farming, environment, chemicals, roadways, disaster, and traffic. We abstracted information from the final set of articles across 6 primary domains: study design; population; exposures evaluated; exposure assessment; CRS definition; and results. Results: We identified 41 articles from 1080 manuscripts: 37 occupational risk papers, 1 environmental risk paper, and 3 papers studying both categories of exposures. None of the 41 studies used a CRS definition consistent with current diagnostic guidelines. Exposure assessment was generally dependent on self-report or binary measurements of exposure based on industry of employment. Only grain, dairy, and swine operations among farmers were evaluated by more than 1 study using a common approach to defining CRS, but employment in these settings was not consistently associated with CRS. The multiple other exposures did not meet quality standards for reporting associations or were not evaluated by more than 1 study. Conclusion: The current state of the literature allows us to make very few conclusions about the role of hazardous occupational or environmental exposures in CRS, leaving a critical knowledge gap regarding potentially modifiable risk factors for disease onset and progression.

Original languageEnglish (US)
Pages (from-to)996-1003
Number of pages8
JournalInternational Forum of Allergy and Rhinology
Volume5
Issue number11
DOIs
StatePublished - Nov 1 2015

Fingerprint

Environmental Exposure
Occupational Exposure
Agriculture
Industry
Paranasal Sinus Diseases
Manuscripts
Air Pollution
Disasters
Occupations
PubMed
Self Report
Disease Progression
Swine
Guidelines
Population
Farmers

Keywords

  • Environmental health
  • Epidemiology
  • Farming
  • Occupational health
  • Sinusitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Otorhinolaryngology

Cite this

Occupational and environmental risk factors for chronic rhinosinusitis : A systematic review. / Sundaresan, Agnes S.; Hirsch, Annemarie G.; Storm, Margaret; Tan, Bruce K.; Kennedy, Thomas L.; Greene, J. Scott; Kern, Robert C.; Schwartz, Brian S.

In: International Forum of Allergy and Rhinology, Vol. 5, No. 11, 01.11.2015, p. 996-1003.

Research output: Contribution to journalArticle

Sundaresan, AS, Hirsch, AG, Storm, M, Tan, BK, Kennedy, TL, Greene, JS, Kern, RC & Schwartz, BS 2015, 'Occupational and environmental risk factors for chronic rhinosinusitis: A systematic review', International Forum of Allergy and Rhinology, vol. 5, no. 11, pp. 996-1003. https://doi.org/10.1002/alr.21573
Sundaresan, Agnes S. ; Hirsch, Annemarie G. ; Storm, Margaret ; Tan, Bruce K. ; Kennedy, Thomas L. ; Greene, J. Scott ; Kern, Robert C. ; Schwartz, Brian S. / Occupational and environmental risk factors for chronic rhinosinusitis : A systematic review. In: International Forum of Allergy and Rhinology. 2015 ; Vol. 5, No. 11. pp. 996-1003.
@article{3672962f095d4f4c8304de512a4a10ca,
title = "Occupational and environmental risk factors for chronic rhinosinusitis: A systematic review",
abstract = "Background: Chronic rhinosinusitis (CRS) is a prevalent and disabling paranasal sinus disease, with a likely multifactorial etiology potentially including hazardous occupational and environmental exposures. We completed a systematic review of the occupational and environmental literature to evaluate the quality of evidence of the role that hazardous exposures might play in CRS. Methods: We searched PubMed for studies of CRS and following exposure categories: occupation, employment, work, industry, air pollution, agriculture, farming, environment, chemicals, roadways, disaster, and traffic. We abstracted information from the final set of articles across 6 primary domains: study design; population; exposures evaluated; exposure assessment; CRS definition; and results. Results: We identified 41 articles from 1080 manuscripts: 37 occupational risk papers, 1 environmental risk paper, and 3 papers studying both categories of exposures. None of the 41 studies used a CRS definition consistent with current diagnostic guidelines. Exposure assessment was generally dependent on self-report or binary measurements of exposure based on industry of employment. Only grain, dairy, and swine operations among farmers were evaluated by more than 1 study using a common approach to defining CRS, but employment in these settings was not consistently associated with CRS. The multiple other exposures did not meet quality standards for reporting associations or were not evaluated by more than 1 study. Conclusion: The current state of the literature allows us to make very few conclusions about the role of hazardous occupational or environmental exposures in CRS, leaving a critical knowledge gap regarding potentially modifiable risk factors for disease onset and progression.",
keywords = "Environmental health, Epidemiology, Farming, Occupational health, Sinusitis",
author = "Sundaresan, {Agnes S.} and Hirsch, {Annemarie G.} and Margaret Storm and Tan, {Bruce K.} and Kennedy, {Thomas L.} and Greene, {J. Scott} and Kern, {Robert C.} and Schwartz, {Brian S}",
year = "2015",
month = "11",
day = "1",
doi = "10.1002/alr.21573",
language = "English (US)",
volume = "5",
pages = "996--1003",
journal = "International Forum of Allergy and Rhinology",
issn = "2042-6976",
publisher = "Wiley-Blackwell",
number = "11",

}

TY - JOUR

T1 - Occupational and environmental risk factors for chronic rhinosinusitis

T2 - A systematic review

AU - Sundaresan, Agnes S.

AU - Hirsch, Annemarie G.

AU - Storm, Margaret

AU - Tan, Bruce K.

AU - Kennedy, Thomas L.

AU - Greene, J. Scott

AU - Kern, Robert C.

AU - Schwartz, Brian S

PY - 2015/11/1

Y1 - 2015/11/1

N2 - Background: Chronic rhinosinusitis (CRS) is a prevalent and disabling paranasal sinus disease, with a likely multifactorial etiology potentially including hazardous occupational and environmental exposures. We completed a systematic review of the occupational and environmental literature to evaluate the quality of evidence of the role that hazardous exposures might play in CRS. Methods: We searched PubMed for studies of CRS and following exposure categories: occupation, employment, work, industry, air pollution, agriculture, farming, environment, chemicals, roadways, disaster, and traffic. We abstracted information from the final set of articles across 6 primary domains: study design; population; exposures evaluated; exposure assessment; CRS definition; and results. Results: We identified 41 articles from 1080 manuscripts: 37 occupational risk papers, 1 environmental risk paper, and 3 papers studying both categories of exposures. None of the 41 studies used a CRS definition consistent with current diagnostic guidelines. Exposure assessment was generally dependent on self-report or binary measurements of exposure based on industry of employment. Only grain, dairy, and swine operations among farmers were evaluated by more than 1 study using a common approach to defining CRS, but employment in these settings was not consistently associated with CRS. The multiple other exposures did not meet quality standards for reporting associations or were not evaluated by more than 1 study. Conclusion: The current state of the literature allows us to make very few conclusions about the role of hazardous occupational or environmental exposures in CRS, leaving a critical knowledge gap regarding potentially modifiable risk factors for disease onset and progression.

AB - Background: Chronic rhinosinusitis (CRS) is a prevalent and disabling paranasal sinus disease, with a likely multifactorial etiology potentially including hazardous occupational and environmental exposures. We completed a systematic review of the occupational and environmental literature to evaluate the quality of evidence of the role that hazardous exposures might play in CRS. Methods: We searched PubMed for studies of CRS and following exposure categories: occupation, employment, work, industry, air pollution, agriculture, farming, environment, chemicals, roadways, disaster, and traffic. We abstracted information from the final set of articles across 6 primary domains: study design; population; exposures evaluated; exposure assessment; CRS definition; and results. Results: We identified 41 articles from 1080 manuscripts: 37 occupational risk papers, 1 environmental risk paper, and 3 papers studying both categories of exposures. None of the 41 studies used a CRS definition consistent with current diagnostic guidelines. Exposure assessment was generally dependent on self-report or binary measurements of exposure based on industry of employment. Only grain, dairy, and swine operations among farmers were evaluated by more than 1 study using a common approach to defining CRS, but employment in these settings was not consistently associated with CRS. The multiple other exposures did not meet quality standards for reporting associations or were not evaluated by more than 1 study. Conclusion: The current state of the literature allows us to make very few conclusions about the role of hazardous occupational or environmental exposures in CRS, leaving a critical knowledge gap regarding potentially modifiable risk factors for disease onset and progression.

KW - Environmental health

KW - Epidemiology

KW - Farming

KW - Occupational health

KW - Sinusitis

UR - http://www.scopus.com/inward/record.url?scp=84954363789&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954363789&partnerID=8YFLogxK

U2 - 10.1002/alr.21573

DO - 10.1002/alr.21573

M3 - Article

C2 - 26077513

AN - SCOPUS:84954363789

VL - 5

SP - 996

EP - 1003

JO - International Forum of Allergy and Rhinology

JF - International Forum of Allergy and Rhinology

SN - 2042-6976

IS - 11

ER -