Occult primary cancer: Clinical practice guidelines

David S. Ettinger; Juan P. Arnoletti; Jon P. Gockerman; Charles Handorf; Kathleen Anne Havlin; Charlotte D. Jacobs; Milind Javle; Larry Kvols; Renato Lenzi; Asif Rashid; Chris A. Rhoades; John A. Ridge; Leonard Saltz; Lawrence N. Shulman; Vernon K. Sondak; John A. Thompson; Przemyslaw Twardowski; Weining Zhen

Occult primary cancer: Clinical practice guidelines

David S. Ettinger, Juan P. Arnoletti, Jon P. Gockerman, Charles Handorf, Kathleen Anne Havlin, Charlotte D. Jacobs, Milind Javle, Larry Kvols, Renato Lenzi, Asif Rashid, Chris A. Rhoades, John A. Ridge, Leonard Saltz, Lawrence N. Shulman, Vernon K. Sondak, John A. Thompson, Przemyslaw Twardowski, Weining Zhen

School of Medicine

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Occult primary tumors, or cancers of unknown primary site, account for 5% to 10% of all diagnosed cancers. These tumors are manifested by a wide variety of clinical presentations, and for most patients, the disease is incurable. Multiple sites of involvement are shown in more than 50% of patients with occult primary tumors. Common sites of involvement are the liver, lungs, bones, and lymph nodes. Life expectancy is very short, with a median survival of about 6 to 9 months. Given the uncertainties and the generally poor prognosis, patients frequently experience significant psychosocial distress, and empathetic discussion about the natural history of these types of cancers and their prognosis is required. Patient and family education, support, and counseling by the primary oncology team and referral to specialized psychosocial services may help to alleviate this distress.

Original language	English (US)
Pages (from-to)	214-233
Number of pages	20
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	3
Issue number	2
State	Published - Mar 2005

Keywords

Carcinoma
Chemotherapy
Diagnosis
Metastasis
NCCN Clinical Practice Guidelines
Occult primary disease

ASJC Scopus subject areas

Oncology

Cite this

Ettinger, D. S., Arnoletti, J. P., Gockerman, J. P., Handorf, C., Havlin, K. A., Jacobs, C. D., Javle, M., Kvols, L., Lenzi, R., Rashid, A., Rhoades, C. A., Ridge, J. A., Saltz, L., Shulman, L. N., Sondak, V. K., Thompson, J. A., Twardowski, P., & Zhen, W. (2005). Occult primary cancer: Clinical practice guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 3(2), 214-233.

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title = "Occult primary cancer: Clinical practice guidelines",

abstract = "Occult primary tumors, or cancers of unknown primary site, account for 5% to 10% of all diagnosed cancers. These tumors are manifested by a wide variety of clinical presentations, and for most patients, the disease is incurable. Multiple sites of involvement are shown in more than 50% of patients with occult primary tumors. Common sites of involvement are the liver, lungs, bones, and lymph nodes. Life expectancy is very short, with a median survival of about 6 to 9 months. Given the uncertainties and the generally poor prognosis, patients frequently experience significant psychosocial distress, and empathetic discussion about the natural history of these types of cancers and their prognosis is required. Patient and family education, support, and counseling by the primary oncology team and referral to specialized psychosocial services may help to alleviate this distress.",

keywords = "Carcinoma, Chemotherapy, Diagnosis, Metastasis, NCCN Clinical Practice Guidelines, Occult primary disease",

author = "Ettinger, {David S.} and Arnoletti, {Juan P.} and Gockerman, {Jon P.} and Charles Handorf and Havlin, {Kathleen Anne} and Jacobs, {Charlotte D.} and Milind Javle and Larry Kvols and Renato Lenzi and Asif Rashid and Rhoades, {Chris A.} and Ridge, {John A.} and Leonard Saltz and Shulman, {Lawrence N.} and Sondak, {Vernon K.} and Thompson, {John A.} and Przemyslaw Twardowski and Weining Zhen",

year = "2005",

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language = "English (US)",

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AU - Ettinger, David S.

AU - Arnoletti, Juan P.

AU - Gockerman, Jon P.

AU - Handorf, Charles

AU - Havlin, Kathleen Anne

AU - Jacobs, Charlotte D.

AU - Javle, Milind

AU - Kvols, Larry

AU - Lenzi, Renato

AU - Rashid, Asif

AU - Rhoades, Chris A.

AU - Ridge, John A.

AU - Saltz, Leonard

AU - Shulman, Lawrence N.

AU - Sondak, Vernon K.

AU - Thompson, John A.

AU - Twardowski, Przemyslaw

AU - Zhen, Weining

PY - 2005/3

Y1 - 2005/3

N2 - Occult primary tumors, or cancers of unknown primary site, account for 5% to 10% of all diagnosed cancers. These tumors are manifested by a wide variety of clinical presentations, and for most patients, the disease is incurable. Multiple sites of involvement are shown in more than 50% of patients with occult primary tumors. Common sites of involvement are the liver, lungs, bones, and lymph nodes. Life expectancy is very short, with a median survival of about 6 to 9 months. Given the uncertainties and the generally poor prognosis, patients frequently experience significant psychosocial distress, and empathetic discussion about the natural history of these types of cancers and their prognosis is required. Patient and family education, support, and counseling by the primary oncology team and referral to specialized psychosocial services may help to alleviate this distress.

AB - Occult primary tumors, or cancers of unknown primary site, account for 5% to 10% of all diagnosed cancers. These tumors are manifested by a wide variety of clinical presentations, and for most patients, the disease is incurable. Multiple sites of involvement are shown in more than 50% of patients with occult primary tumors. Common sites of involvement are the liver, lungs, bones, and lymph nodes. Life expectancy is very short, with a median survival of about 6 to 9 months. Given the uncertainties and the generally poor prognosis, patients frequently experience significant psychosocial distress, and empathetic discussion about the natural history of these types of cancers and their prognosis is required. Patient and family education, support, and counseling by the primary oncology team and referral to specialized psychosocial services may help to alleviate this distress.

KW - Carcinoma

KW - Chemotherapy

KW - Diagnosis

KW - Metastasis

KW - NCCN Clinical Practice Guidelines

KW - Occult primary disease

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AN - SCOPUS:33747585840

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JO - JNCCN Journal of the National Comprehensive Cancer Network

JF - JNCCN Journal of the National Comprehensive Cancer Network

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Occult primary cancer: Clinical practice guidelines

Abstract

Keywords

ASJC Scopus subject areas

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